Autoimmunity in Common Variable Immunodeficiency.

CONCLUSION: Mechanisms producing these conditions are poorly understood but include cytokine and cellular inflammatory pathways, and loss of tolerance to self-antigens through the multiple signaling molecules and pathways common to tolerance and immune deficiency. PMID: 31349011 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research

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This article reviews the phenotypes/endotypes of asthma described in India and the current therapies for management. PMID: 32738847 [PubMed - as supplied by publisher]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusions: Cough is the most frequent presenting complaint in general practice. Infections are the most frequent causes of acute cough regardless of the chest X-ray findings. PMID: 32736491 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
What strategies may help reduce the incidence of healthcare-associated respiratory viral infections? Which are most effective?Current Opinion in Infectious Diseases
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Infectious Diseases Journal Article Source Type: news
CONCLUSION: miR-182-5p mimic therapy inhibits the pathogenic Th17 response in EAU mice. miR-182-5p's inhibition of TAF15 negatively regulates Th17 cell development by suppressing STAT3 phosphorylation. As TAF15 shows a positive relationship with Th17 cell markers in uveitis patients, the miR-182-5p/TAF15 axis shows promise as a therapeutic target for uveitis. PMID: 32736708 [PubMed - as supplied by publisher]
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Tags: Biochem Biophys Res Commun Source Type: research
ConclusionAlthough the immunological and clinical associations between EIMs and CD cannot be fully elucidated, identifying specific relationships of immune-mediated diseases will help to better understand CD pathogenesis.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
AbstractPurpose of reviewA variety of skin diseases are associated with impaired barrier function. The crucial pillars in therapy of previously mentioned conditions are avoidance of triggers, skin protection and individually adapted medical therapy. Until recently, besides of topical corticosteroids, the treatment options were limited. However, a variety of new therapies of skin barrier-related skin diseases became available over the last years. Our goal was to investigate new findings and treatment options in skin diseases with barrier dysfunction, emphasizing on contact dermatitis, hand eczema and atopic dermatitis.Recen...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
Conclusion: We present the characteristics of AIH patients in Central China for the first time. Five microbial biomarkers, including Lachnospiraceae, Veillonella, Bacteroides, Roseburia, and Ruminococcaceae, achieved a high potential distinguishing AIH patients from HCs.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Publication date: Available online 2 July 2020Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Michael Rassner, Johannes Jung, Johanna Schneider, Ralph Wäsch, Monika Engelhardt
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
Publication date: Available online 1 August 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Liat Nachshon, Naama Schwartz, Lior Tsviban, Michael B. Levy, Michael Goldberg, Naama Epstein-Rigby, Yitzhak Katz, Arnon Elizur
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 18 July 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Allison Ramsey, S. Shahzad Mustafa
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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