Potent hERG channel inhibition by sarizotan, an investigative treatment for Rett Syndrome

This study investigated whether sarizotan inhibits hERG potassium channels and prolongs ventricular repolarization.

Source: Journal of Molecular and Cellular Cardiology - July 26, 2019 Category: Cytology Authors: Hongwei Cheng, Chunyun Du, Yihong Zhang, Andrew F. James, Christopher E. Dempsey, Ana P. Abdala, Jules C. Hancox Source Type: research