Triple-negative breast cancer cell line sensitivity to englerin A identifies a new, targetable subtype

ConclusionsThe sensitivity of BT-549 and Hs578T cells to englerin A and digoxin suggests a subset of TNBCs are highly susceptible to cation disruption and encourages investigation of TRPC1 and TRPC4 as potential new biomarkers of sensitivity to cardiac glycosides.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research