Why is Heartburn so Irritating?
I was diagnosed with GERD over two decades ago, so I've had plenty of experience with heartburn, and the work I go through to keep it under control. One of the most irritating things for me about living with GERD and heartburn is not being able to enjoy some of my favorite foods. How about you? Take the poll below and let us know all the ways you find heartburn irritating. And if you want to vent further, you can click on the Comments link below this post.
This article reviews the current literature regarding established and proposed EE-GERD, reporting on all available options for its correct diagnosis and therapeutic management. Expert opinion: MII-pH could help to identify a hidden GERD that causes EE. Unfortunately, standard MII-pH analysis results are often unable to define this association. New parameters such as the mean nocturnal baseline impedance and post-reflux swallow-induced peristaltic wave index may have an improved diagnostic yield, but prospective studies using impedance-pH are needed. PMID: 31322443 [PubMed - as supplied by publisher]
Conclusions: Successful treatment of GER-associated cough may be associated with the attenuation of neurogenic and neutrophilic inflammation. PMID: 31303089 [PubMed - as supplied by publisher]
ConclusionsGEJ opening dynamics attained by EndoFLIP appear to be associated with symptomatic outcomes. When the Dmin and CSA do not decrease by a defined threshold, heartburn is more likely to be severe at 6 or more months postoperatively. This suggests that the fundoplication may not be tight enough to prevent persistent or recurrent GERD.
Infants are often given acid-suppressing medicines to treat gastroesophageal reflux, but the drugs may affect the bones.
AbstractBackgroundGastroesophageal reflux disease (GERD) is present in half of the obese candidates for bariatric surgery. Variability of symptoms and new onset of GERD are often debated. Prior studies have demonstrated that sleeve gastrectomy (SG) is associated with significant weight loss.ObjectivesWe prospectively evaluated the effect of a standardized SG technique on GERD symptoms in 104 patients.MethodsAll patients were surveyed on the presence of heartburn and/or regurgitation with a specific questionnaire (GERD-HRQL). Esophagogastroduodenoscopy (EGDS) was performed in the preoperative phase and after 12 months...
CONCLUSION: The majority of GPs and otolaryngologists do not believe themselves to be sufficiently informed about LPR, leading to different practice patterns and grey areas. The elaboration of international recommendations in the management of reflux is needed to improve practices. PMID: 31257901 [PubMed - as supplied by publisher]
Purpose of review Gastroesophageal reflux disease (GERD) is primarily a motor disorder, but its pathogenesis is multifactorial. Although gastric acid secretion is usually normal in GERD patients, treatment with proton pump inhibitors (PPIs) has become the standard of care, despite increasing awareness of their shortcomings. In this article, a new class of antisecretory drugs (namely potassium-competitive acid blockers, P-CABs), developed to overcome these limitations, is discussed. Recent findings P-CABs block the K+ exchange channel of the proton pump, resulting in rapid, competitive, reversible inhibition of acid se...
(Wiley) Individuals who are obese often experience heartburn and other symptoms of acid reflux. Previous research indicates that gastric bypass surgery for obesity helps alleviate symptoms in the short term, but a new Alimentary Pharmacology&Therapeutics study finds that these benefits often are not long-lasting.
New research finds a link between proton pump inhibitors and heightened risk of death from heart disease, kidney disease, and stomach cancer.
CONCLUSION: The QoLRAD test measuring quality of life, except some subdomains in our study that we performed on patients diagnosed with GERD, was found to be valid and reliable. PMID: 31144656 [PubMed - in process]