Association of metabolic syndrome with chronic kidney disease in premenopausal and postmenopausal women.

CONCLUSIONS: MS is correlated with CKD in both premenopausal and postmenopausal women, and the association is dependent on diabetes, hypertension, and hyperuricemia in premenopausal women but not in postmenopausal women. PMID: 31340922 [PubMed - in process]
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

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Publication date: Available online 21 September 2019Source: PeptidesAuthor(s): Camilla F. Thomsen, Mathias Ried-Larsen, Jens P. Goetze, Lars B. Andersen, Jens Faber, Anders Grøntved, Jørgen L. JeppesenAbstractAtrial natriuretic peptide (ANP) is known for its natriuretic, diuretic, and vasodilatory properties. However, ANP also has metabolic effects stimulating lipolysis and lipid oxidation. Overweight individuals have decreased circulating ANP concentrations. It has been proposed that this potential ANP deficiency could have biological consequences in overweight-related disorders, including decreased lipolysi...
Source: Peptides - Category: Biochemistry Source Type: research
Publication date: February 2020Source: The Journal of Chemical Thermodynamics, Volume 141Author(s): Fernando Hevia, Juan Antonio González, Ana Cobos, Isaías García de la Fuente, L.F. SanzAbstractRelative permittivities at 1 MHz, εr, at 0.1 MPa and (293.15–303.15) K and refractive indices, nD, at similar conditions have been measured for the alkan-1-ol (methanol, propan-1-ol, butan-1-ol, pentan-1-ol or heptan-1-ol) + N,N-diethylethanamine (TEA) systems. Positive values of the excess permittivities, εrE, are encountered for the methanol system at high alcohol concentration...
Source: The Journal of Chemical Thermodynamics - Category: Chemistry Source Type: research
It's no secret that there's a multitude of unhappy nurses out there in the world. From mandatory overtime to unhealthy nurse-patient ratios, I admit there are very valid reasons for this seeming epidemic of discontent. So, is the nursing glass half-full or half-empty? I guess it depends on who you're drinking with (and perhaps what you're drinking). Photo by Jana Sabeth on UnsplashReasons To Be Cheerful---Or NotThis blog post isn't really about the aforementioned multitude of reasons that explain nurses'rampant unhappiness. A new study mentioned recently on Twitter states that a full one-third of nurses...
Source: Digital Doorway - Category: Nursing Tags: nurse nurse identity nurses nursing nursing careers nursing identity Source Type: blogs
Hepcidin protects pulmonary artery hypertension in rats by activating NF-κB/TNF-α pathway. Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7573-7581 Authors: Liu WY, Wang L, Lai YF Abstract OBJECTIVE: The pulmonary artery hypertension (PAH) model was established in rats in this study. Therefore, we aimed to elucidate the protective role of Hepcidin in PAH rats and its underlying mechanism. MATERIALS AND METHODS: 24 male Sprague Dawley (SD) rats were randomly divided into sham group, PAH group and Hepcidin group, with 8 rats in each group. After animal procedures, hemodynamic parameters and r...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CONCLUSIONS: Our study firstly established that the G allele and C/G genotype of rs184187143 single nucleotide polymorphism (SNP) in SLC26A6 gene was closely linked with the increased risk for the development of the diabetic ketoacidosis of GDM. PMID: 31539142 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CONCLUSIONS: TUG1 is downregulated in DN. The overexpression of TUG1 could suppress the proliferation and ECM accumulation of mesangial cells via inhibiting the PI3K/AKT pathway. PMID: 31539141 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
We report a case of septic shock caused by this pathogen. A 78-year-old man affected by diabetes and hypertension was admitted for fever in our Emergency Department. He reported fever (37.7°C) with normal values of blood pressure, heart rate and saturation of oxygen. Laboratory studies showed increased values of procalcitonin and normal white-cell level. Blood cultures were collected and an empirical antibiotic therapy was started. He reported six days earlier a bite of a dog at the right hand. During the following days the patient presented a deterioration of clinical conditions with fever, asthenia and comparison of ...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Spontaneous Model of Sjögren's Syndrome in NOD Mice. Curr Protoc Pharmacol. 2019 Sep;86(1):e65 Authors: Scuron MD, Fay B, Oliver J, Smith P Abstract The non-obese diabetic (NOD) mouse model is the most widely described and validated method for investigating human primary Sjögren's syndrome (SS) and represents a useful model for translational studies. However, the systemic disease manifestation in NOD mice is sensitive to the housing environment, as stress modulates the immune system, so it is essential to confirm that readouts are robust, reproducible, and sensitive to known clinical treatmen...
Source: Current Protocols in Pharmacology - Category: Drugs & Pharmacology Tags: Curr Protoc Pharmacol Source Type: research
CONCLUSION: The results shows curcumin has not a significant effect on cathepsin D level in patients with MetS. PMID: 31538907 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
ConclusionsGöttingen Minipigs fed CDAHFD developed pronounced steatosis with inflammation around steatotic hepatocytes and incipient fibrosis, thereby showing potential as a model for human NASH. Further studies are needed to investigate the period needed for marked fibrosis to develop.
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
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