Retrograde signaling disruption influences ABC superfamily transporter, ergosterol and chitin levels along with biofilm formation in Candida albicans

Conclusion: Present study establishes a link between RTG signaling, drug efflux and biofilm formation and validates CaRTG3 as antifungal target. Intricate studies are needed to further understand and exploit this therapeutic opportunity.
Source: Journal of Medical Mycology - Category: Biology Source Type: research