Can digital X-ray radiogrammetry be an alternative for dual-energy X-ray absorptiometry in the diagnosis of secondary low bone quality in children?

Conclusion: DXR correlates well with as well DXALS as bone age-adjusted DXALSZ-scores and shows good agreement with as well DXALS as bone age-adjusted DXALSZ-scores ≤ − 2.0. DXR shows best results when compared with DXALSZ-scores.What is Known:• Digital X-ray radiogrammetry (DXR) may correlate well with dual-energy X-ray absorptiometry (DXA) in pediatric, adolescent, and adult patients.• DXR is a feasible method for assessment of bone quality in children.What is New:• This is the first prospective study in children with suspected secondary low bone quality that illustrates correlation between DXR and bone age-adjusted DXA Z-scores and that shows good agreement between DXR and DXA as bone age-adjusted DXA Z-scores ≤ −2.0.• Our results suggest DXR to be a good alternative for DXA for determining low bone quality.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research