Nocebo effects of a simplified package leaflet compared to unstandardised oral information and a standard package leaflet: a pilot randomised controlled trial

ConclusionsThis pRCT provides the first hints on the way information on AEs is reported in PILs can affect the nocebo effect. This pRCT shows that a definitive RCT is feasible. If the results are confirmed in a definitive large RCT, a revision of the current practice for designing PILs should be considered.Trial registrationClinicalTrials.gov identifier:NCT03428035. Registered 2 February 2018.

http://link.springer.com/10.1186/s13063-019-3565-3

Source: Trials - July 25, 2019 Category: Research Source Type: clinical trials