Device for Opioid Overdoses Releases Naloxone Automatically

Opioids can bind to brain receptors that are responsible for breathing, causing hypoventilation, and all too frequently leading to death in those that overdose. Naloxone (aka Narcan) is an antidote that prevents opioids from binding to brain receptor...
Source: Medgadget - Category: Medical Devices Authors: Tags: Emergency Medicine Source Type: blogs

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This study describes the prevalence of nonmedical methadone use in a community sample of PWID and examines factors associated with recent use of nonmedical methadone. Methods: A cross-sectional sample of PWID (N = 777) was recruited using targeted sampling and interviewed in California (2011-2013). Descriptive, bivariate, and multivariate logistic regression analyses were used to determine characteristics associated with nonmedical methadone use in the last 30 days. To determine if nonmedical methadone use was associated with overdose in the last 6 months, a separate multivariate analysis was conducted...
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
This study aimed to examine if an educational intervention impacted college students' attitudes towards prescription opioid drugs (POD). Methods: Two hundred forty-two participants (72 males, 21 ± 3 years) from an American university participated. After collecting demographic data (questionnaire 1; Q1), investigators recited a narrative in which the protagonist was injured and prescribed POD. Next, participants rated their agreement on 10 Likert prompts and two visual analog scales (VAS) before (Q2) and after (Q3) an educational intervention, then noted (Q4) which topics were most or least influ...
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
In 1819, a soon-to-be-knighted John Herschel (1792 to 1871) discovered that hyposulfite of soda could “fix” or make photographic images permanent by dissolving away unexposed and otherwise insoluble silver salts. This British genius soon coined terms for his astronomical or botanical images as “negatives” or “positives” and for the art as “photography.” Even after it was renamed sodi um thiosulfate, hyposulfite of soda retained photographers’ nickname for it: “hypo.” An antidote for cyanide poisoning, sodium thiosulfate was supplied in ampoules to physicians...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Condition:   Food Allergy Intervention:   Other: Amino Acid-Based Experimental Study Formula Sponsor:   Abbott Nutrition Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Allergy Intervention:   Diagnostic Test: Skin Testing Sponsor:   Mayo Clinic Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionThis antimicrobial stewardship intervention can be used to provide patients with reported antibiotic allergy labels with the preferred antibiotic treatment and to de-label them after uneventful re-exposure to the antibiotic agent.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Date: Wednesday, 11 13, 2019; Speaker: Jason Brenchley, Ph.D., Senior Investigator, Barrier Immunity Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases; Building: Building 45 (Natcher Building); Ruth Kirschstein Auditorium
Source: NIH Calendar of Events - Category: American Health Source Type: events
‚ÄčThe atomizer is a handy tool to instill life-saving medication into the nose, and you should consider stocking them if you don't already. An atomizer can be used to administer naloxone and countless other drugs as well as for moderate sedation and pain control. Pediatric and adult patients alike can benefit from intranasal fentanyl or Versed. Studies on intranasal epinephrine for anaphylaxis also look promising, but it does require a higher dose—5 mg instead of 0.3 mg. (Asian Pac J Allergy Immunol 2016;34[1]:38; http://bit.ly/2Prpjhb.)The atomizer is easy to use and can be attached to any syringe. Each spray creat...
Source: The Procedural Pause - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Management of acetaminophen toxicity typically involves administering N-acetylcysteine (NAC) in order to prevent hepatic injury. While NAC is considered the gold standard of therapy, it is also associated with risk of non-immunologic anaphylaxis. This case illustrates a less commonly recognized reaction to NAC and provides an opportunity to review management of acetaminophen toxicity in patients who demonstrate such a reaction.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: M057 Source Type: research
This study aimed to determine the clinical value, and potential cardiovascular harm, on elderly patients with anaphylaxis who received intramuscular (IM) and IV epinephrine. Over a five-year period, the researchers examined the ED record of anaphylactic patients over the age of 50 who were transported to two urban EDs. They compared the clinical outcome and cardiovascular complications between younger and older adults who received epinephrine for anaphylaxis. Of the 2,995 patients with allergy-related complaints, 492 were treated for anaphylaxis. Of them, 122 (24.8%) were older adults. Only 36.1% of the older patients rece...
Source: JEMS Patient Care - Category: Emergency Medicine Authors: Tags: Patient Care Columns Source Type: news
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