Isolation, biochemical characterization and antiparasitic activity of BmatTX-IV, a basic Lys49-phospholipase A2 from the venom of Bothrops mattogrossensis from Paraguay.

CONCLUSION: Physicochemical and biological characterization of snake venoms components is critically important, since these complex mixtures provide a source of molecules with antiparasitic potential, making further studies necessary to identify and characterize components with higher efficacy and selectivity.
PMID: 31340737 [PubMed - as supplied by publisher]

Source: Current Topics in Medicinal Chemistry - July 22, 2019 Category: Chemistry Authors: Alfonso JJ, Kayanoa AM, Garay AFG, Simões-Silva R, Sobrinho JC, Vourliotis S, Soares AM, Calderon LA, Gómez MCV Tags: Curr Top Med Chem Source Type: research