Evaluation of Carcinogenic Risks Related to Nitrate Exposure in Drinking Water in Iran

Publication date: Available online 24 July 2019Source: MethodsXAuthor(s): Mohammad Darvishmotevalli, Maryam Moradnia, Mohammad Noorisepehr, Ali Fatehizadeh, Saeid Fadaei, Hamed Mohammadi, Mehdi Salari, Hamzeh Ali Jamali, Seyede Shahrbanoo DanialiAbstractNitrate is one of the most important contaminants that can release into the environment predominantly as a result of anthropogenic processes. Excessive intake of nitrates may increase the risk of certain types of cancer. The aim of this study was to investigate the concentration of nitrate in drinking water and its health to people in Iran. This cross-sectional study has performed in 2019. Nitrate concentrations in drinking water supplies were obtained from peer-reviewed publications. Monte Carlo stimulations and mathematical models were used to determine the excess cancer risk. Risk level for assessing the carcinogen risk was 10‐5 (1 per 100000 persons). Nitrate concentrations and cancer risk related to nitrate were classified by GIS software. According to the obtained results, the drinking water supplies of Tehran, Mashhad (Khorasan Razavi), Zahedan (Sistan and Baluchestan), Shiraz (Fars), Qom, Ardabil and Ahwaz (Khuzestan) have higher nitrate concentrations than the limit recommended by WHO and Institute of Standards and industrial Research of Iran (ISIRI). The estimated cancer risks for the provinces of Tehran, Mashhad (Khorasan Razavi), Zahedan (Sistan and Baluchestan), Shiraz (Fars), Qom, Ardabil and Ahwaz (Khuzestan) ...
Source: MethodsX - Category: Science Source Type: research