Cutaneous Photoprotective Activity of a Short ‐term Ingestion of High‐Flavanol Cocoa: A Nutritional Intervention Study

In vivo and in  vitro studies have shown that prolonged oral administration of flavanol‐rich cocoas extracts have photoprotective effects. We demonstrated that one‐week administration of 4–6 g of a new variety of naturally selected cocoa extract, rich in bioactive compounds, retains a dose‐dependent phot oprotective effect. This extract induced a statistically significant increase in the visual erythema threshold and a significant reduction in the “a” parameter. These results are also indicative of the fact that topical sunscreens could be supplemented by a specific diet. AbstractIn vivo andin  vitro studies have shown that prolonged oral administration of flavanol ‐rich cocoas extracts have photoprotective effects. The aim of the present study was to assess the photoprotective activity of short‐time administration of a new variety of naturally selected cocoa extract rich in bioactive compounds. We selected a cocoa powder particularly rich in polyphenols, flavanols, caffeine, theobromine and theophylline. We then investigated, in 10 healthy subjects, the photoprotective effects of one week of daily oral administration of two doses of such powder. Phototesting with solar simulated radiation was performed at baseline and after cocoa supplementation. Vi sual assessment of the minimal erythema dose and spectrophotometric measurement of the “a” parameter were done after 24 h from the irradiation. Oral daily supplementation of 1 g of high‐flavanol cocoa w...
Source: Photochemistry and Photobiology - Category: Science Authors: Tags: Research Article Source Type: research