Association of Genetic Variations in NRF2, NQO1, HMOX1, and MT with Severity of Coronary Artery Disease and Related Risk Factors.

In conclusion, NRF2 rs6721961 associated with CAD and severity of coronary atherosclerosis. NQO1 rs1800566 also associated with CAD, only in female. Combined polymorphisms of three NRF2-regulated genes increased risk of DM and hypertension. PMID: 31332605 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31332605?dopt=Abstract

Source: Cardiovascular Toxicology - July 21, 2019 Category: Cardiology Authors: Sarutipaiboon I, Settasatian N, Komanasin N, Kukongwiriyapan U, Sawanyawisuth K, Intharaphet P, Senthong V, Settasatian C Tags: Cardiovasc Toxicol Source Type: research