Tryptophan catabolism increases in breast cancer patients compared to healthy controls without affecting the cancer outcome or response to chemotherapy

Indoleamine 2,3-dioxygenase catalyzes the conversion of tryptophan to kynurenine, an immunosuppressive metabolite involved in T regulatory cell differentiation. Indoleamine 2,3-dioxygenase is expressed in many...

Source: Journal of Translational Medicine - July 23, 2019 Category: Research Authors: Concetta Elisa Onesti, Fran çois Boemer, Claire Josse, Stephane Leduc, Vincent Bours and Guy Jerusalem Tags: Research Source Type: research