Comparison of the effectiveness of pain control with two regimens of acetaminophen following uncomplicated intra-alveolar extraction: Olawole W.O1, Okoje V.N1, Ibikunle A.A2, Arotiba J.T1

This study compared the effectiveness of post-extraction pain control using two regimens of paracetamol. Subjects were randomly distributed into two groups; subjects in group A had postoperative oral administration of acetaminophen 1 g 2 h after the extraction and then 1 g every 8 h for 24 h, while subjects in group B had extended postoperative oral administration of acetaminophen. Thereafter, subjects recorded their postoperative pain experiences. Data were analyzed using IBM SPSS Statistics for Windows version 20. Level of statistical significance was set at P < 0.05. Data from 200 subjects were analyzed. An overall male/female ratio of 1:1.2 and a mean (±SD) age of 44.27 (16.09) years were observed. A comparison of pain experience between groups at all evaluation points revealed no statistically significant difference (p > 0.05). Also, the type and number of teeth extracted exerted no statistically significant influence on pain experience (p > 0.05). There was no significant difference between the effectiveness of post-extraction pain control using the two paracetamol regimens. Therefore, extended administration of paracetamol may be unwarranted.
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research