Aspirin desensitization or biologics for AERD?

Aspirin-exacerbated respiratory disease (AERD) is a syndrome characterized by asthma that is often severe with progressive airway remodeling, the presence of eosinophilic chronic sinusitis with nasal polyp (CRSwNP) formation, and intolerance to aspirin and other non-selective cyclooxygenase 1 (COX-1) inhibitors.1 The prevalence of AERD in the general population is 1% which increases to 7% amongst those with asthma. In the most severe cases, ingestion of aspirin can trigger systemic reactions and even death.

Source: Annals of Allergy, Asthma and Immunology - July 22, 2019 Category: Allergy & Immunology Authors: John W. Steinke Tags: Perspective Source Type: research