Impaired cognitive self-awareness mediates the association between alexithymia and excitation/inhibition balance in the pgACC.

CONCLUSION: Our results corroborate the importance of the pgACC as a mediating region of alexithymia, reflected in an altered E/I balance. Furthermore, we could specify that this altered balance is linked to a GABA-related modulation of cognitive self-awareness of emotions.
PMID: 31328716 [PubMed - as supplied by publisher]

Source: Psychological Medicine - July 21, 2019 Category: Psychiatry Authors: Kühnel A, Widmann A, Colic L, Herrmann L, Demenescu LR, Leutritz AL, Li M, Grimm S, Nolte T, Fonagy P, Walter M Tags: Psychol Med Source Type: research