Osteocyte numbers decrease only in postcranial but not in cranial bones in humans of advanced age.

CONCLUSIONS: Considering differences and commonalities regarding the bone samples, such as loading, mechanisms of ossification or the surrounding stromal cell compartment, our findings indicate that positional information laid down during ontogenetic processes is instructive during the entire life thus potentially also moulding spatial-specific mechanistic distinctions of bone aging.
PMID: 31330307 [PubMed - as supplied by publisher]

Source: Annals of Anatomy - July 18, 2019 Category: Anatomy Authors: Stigler RG, Becker K, Hasanov E, Hörmann R, Gassner R, Lepperdinger G Tags: Ann Anat Source Type: research