A di-iron protein recruited as an Fe[II] and oxygen sensor for bacterial chemotaxis functions by stabilizing an iron-peroxy species [Chemistry]
Many bacteria contain cytoplasmic chemoreceptors that lack sensor domains. Here, we demonstrate that such cytoplasmic receptors found in 8 different bacterial and archaeal phyla genetically couple to metalloproteins related to β-lactamases and nitric oxide reductases. We show that this oxygen-binding di-iron protein (ODP) acts as a sensor for chemotactic responses...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Alise R. Muok, Yijie Deng, Vadim M. Gumerov, Jenna E. Chong, Jennifer R. DeRosa, Kurni Kurniyati, Rachael E. Coleman, Kyle M. Lancaster, Chunhao Li, Igor B. Zhulin, Brian R. Crane Tags: Biological Sciences Source Type: research