Efficacy of 1064 Q switched Nd:YAG laser in the treatment of oral lichen planus.

This study aimed to examine the effectiveness of Nd:YAG laser in the treatment of long-standing erosive-atrophic OLP. Patients and methods: Twenty-four patients diagnosed with OLP were included in this study. A total of 59 lesions was assessed as regards to the degree of pain by visual analog scale and clinical scores by Thongprasom sign scoring system before and after treatment. All patients were treated by Nd:YAG laser therapy with (1064 nm 0.5 W, 30 s, 1.2 J/cm2) three times weekly and for 1 month. Treatment efficacy index was determined after the end of therapy. Results: A significant pain reduction was detected after Nd:YAG laser treatment (p 
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research

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Background: Oral lichen planus (OLP) is a chronic disease without any definitive treatment. Localcorticosteroids are often prescribed, but their efficacy has been questioned by many studies. Thepurpose of this study was to investigate the effect of nano ‑based triamcinolone acetonide gel (NT)and compare it with conventional triamcinolone gel (CT) on OLP.Materials and Methods: In this triple ‑blind randomized clinical trial study, 40 patients with ErosiveOLP were divided into two groups receiving (CT) and (NT). The patients were requested to applythem four times a day for 2 weeks. The severity of pain was evaluated thro...
Source: Dental Research Journal - Category: Dentistry Source Type: research
Lichen planus is a common inflammatory skin disease, it usually affects the trunk, flexural surfaces, and oral or genital mucosa. Eye lids are rarely affected with few reported cases. Here we present a 67-year-old woman who has itchy skin eruption confined to the eyelids for 3 months. No history of using cosmetics. No personal or family history of atopy. No history of joint pain, weakness, or fatigue. On examination, the patient had violaceous thin scaly plaques over both eye lids. Oral mucosa is free and no other lesions on the body.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
CONCLUSIONS: TENS is beneficial in the field of dermatology, particularly involving the relief of chronic pruritus. PMID: 31418608 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
Publication date: Available online 13 August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Paolo J. Fantozzi, Nathaniel Treister, Revathi Shekar, Sook-Bin Woo, Alessandro VillaAbstractObjectivesTo report on the clinical indications and treatment outcomes of intralesional steroid therapy (IST) for oral ulcerative conditions in an oral medicine practice.Study DesignA retrospective single-center study of patients with oral ulcerative conditions who were treated with IST. Demographic data, clinical diagnosis of the oral condition, size of the ulcer and pain were abstracted from electronic...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
ConclusionSince CUS has overlapping clinical, histological, and immunofluorescence features with lichen planus and vesiculobullous diseases, clinicians and pathologists should consider this unusual, but significant, entity whenever oral ulcerative diseases with mixed features are encountered.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
ConclusionThe application of HA is suggested, and is an effective substitute for TA in the treatment of OLP.
Source: Journal of Investigative and Clinical Dentistry - Category: Dentistry Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conclusions The clinical trials discussed here, which include several trials investigating novel therapeutic targets, demonstrate that translational research in pemphigus and pemphigoid is a fast-growing field. We thus expect that several novel treatments will be shortly available for the treatment of pemphigus and pemphigoid patients. Given the high, and thus far unmet, medical need in this field (110), this is highly encouraging and will hopefully improve the quality of life of the affected patients. In addition to the compounds and targets described here, several new targets have been recently identified in preclinical...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionGreater severity of OLP and OLL seems to be associated with increased levels of anxiety, higher scores of oral health impact profile, and decreased QoL.Clinical relevancePatients with severe OLP/OLL may benefit from additional therapeutic treatments, such as psychological and/or psychiatric management, concomitant to treatment specific to oral lesions.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
ConclusionAgranulocytosis or pancytopenia usually developed within 2 months after levamisole treatment, but it might be delayed. Agranulocytosis was more likely to occur in females and onset was acute. Levamisole is an effective immunomodulator for OLP patients; however, it should be used with caution and administered with regular blood monitoring.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
CONCLUSION: Agranulocytosis or pancytopenia usually developed within 2 months after levamisole treatment, but it might be delayed. Agranulocytosis was more likely to occur in females and onset was acute. Levamisole is an effective immunomodulator for OLP patients; however, it should be used with caution and administered with regular blood monitoring. PMID: 30922614 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - Category: General Medicine Authors: Tags: J Formos Med Assoc Source Type: research
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