Evaluation of satisfaction with three different cervical cancer screening modalities: clinician-collected Pap test vs. HPV test by self-sampling vs. HPV test by urine sampling.

CONCLUSIONS: Korean women were more likely to report satisfaction with alternative modalities (self-sampling and urine sampling) for CCS in comparison to the Pap test. This suggests that self-collected modalities may help with improving CCS uptake rates by eliminating burden related with the Pap test. However, further studies for test accuracy and cost-effective analysis of the alternative modalities should be conducted in order to apply CCS. PMID: 31328458 [PubMed - in process]
Source: Journal of Gynecologic Oncology - Category: OBGYN Tags: J Gynecol Oncol Source Type: research

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Publication date: Available online 20 September 2019Source: Biocybernetics and Biomedical EngineeringAuthor(s): Tasleem Kausar, MingJiang Wang, Muhammad Idrees, Yun LuAbstractAmong the predominant cancers, breast cancer is one of the main causes of cancer deaths impacting women worldwide. However, breast cancer classification is challenging due to numerous morphological and textural variations that appeared in intra-class images. Also, the direct processing of high resolution histological images is uneconomical in terms of GPU memory. In the present study, we have proposed a new approach for breast histopathological image ...
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
This study is to compare the cleaning effectiveness of two Ni-Ti files systems. Thirty single-rooted human teeth were selected and two NiTi rotary systems were used. Group A: canal shaping with ProTaper® Universal (Dentsply Tulsa Dental Specialties, Tulsa, OK) (PTU); Group B: (n=15) canal shaping with Mtwo Ni-Ti instruments (Sweden and Martina, Padova, Italy) and apical finishing with Mtwo Apical Ni-Ti instruments (Sweden and Martina, Padova, Italy). The amount of debris and smear layer were quantified on a basis of a numerical evaluation scale. The data established for scoring the debris and the smear layer was record...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
This study was aimed at detecting NRAS G12D and NRAS G13C mutant genes among apparently healthy and haematologic malignant individuals, and to explore their association with some clinical and demographic factors as well as disease status and progression. A total of 200 cfDNAs, 100 each from haematologic malignant patients and blood donors, respectively, were analyzed for the presence of NRAS gene mutations in codons 12 and 13. These mutations were tested using multiplex allele-specific PCR (AS-PCR). The mutations were detected by selective amplification using mutation-specific synthetic oligonucleotides. NRAS G12D and NRAS...
Source: Journal of Immunoassay and Immunochemistry - Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research
This study was carried out with samples belonging to 140 horses residing in Spain and showing common clinical signs of EP. A blood smear microscopic examination and a comparison between the different results obtained by competitive Enzyme-Linked Immunosorbent Assay (cELISA), real-time Polymerase Chain Reaction (PCR) and hematological and biochemical (direct and total bilirubin) screening were conducted. EP positivity rates by cELISA and PCR were 50.7% and 42.9%, respectively, whereas only 9% of the horses were positive in the microscopic analysis. A significantly higher number of B. caballi-positive horses were detected by...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Publication date: Available online 20 September 2019Source: Biosensors and BioelectronicsAuthor(s): Zhen Rong, Zikun Bai, Jianing Li, Hao Tang, Tianyi Shen, Qiong Wang, Chongwen Wang, Rui Xiao, Shengqi WangAbstractSimultaneous detection of free and complexed prostate-specific antigen (f-PSA and c-PSA) is critical to the prostate cancer (PCa) diagnostic accuracy for clinical samples with PSA values in the diagnostic gray zone between 4 and 10 ng mL−1. Herein, red and green magnetic-quantum dot nanobeads (MQBs) with superior magnetic property and high luminescence were fabricated via polyethyleneimine-intermediated...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: 15 January 2020Source: Journal of Molecular Structure, Volume 1200Author(s): Xingxing Gao, Guidong Gong, Zhonghui Zhang, Guoyuan Du, Yuan Cao, Gang ZhaoAbstractThe cyclopalladated compound (−)-(Sp,R,R,Sp)-3 was obtained by the reaction between acetylferrocene and chiral amines (+)-R-1, followed by palladium acetate and sodium nitrite. (−)-(Sp,R,R,Sp)-3 was characterized by 1H, 13C NMR and ESI-MS. The absolute configuration of the compound (−)-(Sp,R,R,Sp)-3 is determinated by single crystal diffraction. It is found that the compound (−)-(Sp,R,R,Sp)-3 (IC50 = 0.15 μM, 0.49...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 20 September 2019Source: Chemico-Biological InteractionsAuthor(s): Alina Hanf, Matthias Oelze, Adrian Manea, Huige Li, Thomas Münzel, Andreas DaiberAbstractThe anthracycline doxorubicin (DOX) is widely used in cancer therapy with the limitation of cardiotoxicity leading to the development of congestive heart failure. DOX-induced oxidative stress and changes of the phosphoproteome as well as epigenome were described but the exact mechanisms of the adverse long-term effects are still elusive. Here, we tested the impact of DOX treatment on cell death, oxidative stress parameters and exp...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Authors: Nuhmani S Abstract Patellar tendinopathy, or jumper's knee is a common musculoskeletal condition characterized by progressive activity-related pain on the anterior aspect of the knee and tenderness on the patellar tendon. A conservative method is often the first choice of treatment, which can include anti-inflammatory medication, injection therapies, physiotherapy, eccentric exercises, extra corporeal shock wave therapy, orthosis, etc. Although there are several treatment options available, the management of patellar tendinopathy is still controversial. The literature reveals many different injection metho...
Source: The Physician and Sportsmedicine Online - Category: Sports Medicine Tags: Phys Sportsmed Source Type: research
Conclusions. This study identified the unique role of demographic and clinical variables in mental illness stigma among patients with schizophrenia. Nurses should consider these variables when implementing anti-stigma intervention programs. Impact Statement Both clinical and demographic variables are associated with perceived stigma toward mental illness among patients diagnosed with schizophrenia. PMID: 31535959 [PubMed - as supplied by publisher]
Source: Contemporary Nurse - Category: Nursing Tags: Contemp Nurse Source Type: research
“I’m nervous. I’m pretty much always nervous,” I repeatedly told every doctor and nurse who asked me how I was doing before my surgery. When you’re 32 and your pre-op nurse describes you as healthy, it doesn’t dispel all the thoughts that fill your head as you stare at the drop ceiling tiles at the surgery center. “Is this real? How is this my life? What am I doing here?” Those are the kinds of thoughts that usually precede a panic attack for me. But I breathed deeply and stayed in the moment. “Soon this will be over,” I told myself, “and then you can finall...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Health-related Personal Sports Stress Trauma anxiety Cervical Cancer Cervical intraepithelial neoplasia Child Abuse child molestion Exercise healing Healthy Eating HPV Human papillomavirus Immune System moderate cervical dy Source Type: blogs
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