Surgical excision is the gold standard for a correct diagnosis of carotid paragangliomas

Bobadilla-Rosado et al1 reported, in their recent and interesting article, their retrospective experience in the surgical treatment of carotid paragangliomas, in particular bilateral ones. They describe 8 patients with bilateral laterocervical masses (16 neoplasms, of which 2 are malignant, in patients 3 and 7, respectively). There are no definitive, well-accepted, reproducible histological criteria for malignancy in carotid body tumours. The histological features include necrosis, extensive capsular or vascular invasion, increased mitotic activity, cellular atypia, loss of the well-differentiated zellbalen pattern and tumour spindling.

Source: Annals of Vascular Surgery - July 21, 2019 Category: Surgery Authors: Antonio Bozzani, Vittorio Arici, Mauro Rossi, Chiara Spialtini, Franco Ragni Source Type: research