Efficient Nanocarriers of siRNA Therapeutics for Cancer Treatment

Nanocarriers as drug delivery systems are promising and becoming popular, especially for cancer treatment. In addition to improving the pharmacokinetics of poorly soluble hydrophobic drugs by solubilizing them in a hydrophobic core, nanocarriers allow cancer-specific combination drug deliveries by inherent passive targeting phenomena and adoption of active targeting strategies. Nanoparticle-drug formulations can enhance the safety, pharmacokinetic profiles and bioavailability of locally or systemically administered drugs, leading to improved therapeutic efficacy.
Source: Translational Research - Category: Research Authors: Source Type: research