Some Women Don't Heed Warnings of Acne Drug Danger During Pregnancy Conception Some Women Don't Heed Warnings of Acne Drug Danger During Pregnancy Conception

It's long been known that the highly effective acne medication isotretinoin is tied to the risk of severe birth defects. But even with a special program in place to prevent conception in women taking the drug, each year 200 to 300 women in the U.S. become pregnant while taking it, a new study shows.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Dermatology News Source Type: news

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We present herein a 20-year-old woman with multiple vulvar condylomata acuminata who developed EN two weeks after onset of oral isotretinoin therapy. To the best of our knowledge, this is the first report of EN occurring during isotretinoin treatment in a patient without acne and strongly indicates that the pathogenesis of EN can be directly related to the biological actions of isotretinoin. Erythema nodosum should be regarded as a rare...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
In the midst of this coronavirus pandemic, a friend of mine relayed a troubling story to me recently. My friend is a dermatologist who is 9-months pregnant, living and working in a county with no known community spread of the novel coronavirus.  After spending time examining a 19-year-old with acne, the patient told her that she […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs
Here’s another excerpt from my new Revised &Expanded Edition of Wheat Belly, taken from chapter 16, Mr. and Mrs. Wheat Belly: LOOK DOWN AND YOU SHOULD immediately get an idea of where your sexual preferences lay. Well, at least a rough idea. The unnatural situation created when humans try to consume the seeds of grasses, packed with disrupters of human hormones, undo some of those anatomical, pre-programmed tendencies. Once again, eating things that should never have made it onto the human dietary menu defies the script written into our genetic codes, expressed as painful menstrual cycles, excessive body hair, in...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open Source Type: blogs
AbstractAcne vulgaris is the most common skin disease treated by dermatologists. It can be severe and result in permanent scars. Isotretinoin is the most effective treatment for acne and has the potential for long-term clearance. Prescribing and monitoring protocols can vary widely among prescribers. Recent studies, reports, and consensus statements help shed light on optimizing the use of isotretinoin for acne. A recent literature review is summarized in this article to help the practitioner optimize isotretinoin use for acne. The article outlines the advantages and disadvantages of standard, high-dose, and low-dose isotr...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
AbstractIntroductionThe study was conducted to assess the safety and efficacy of a combined oral contraceptive, YAZ, containing 3  mg drospirenone/20 μg ethinyl estradiol administered in a 24/4 regimen.MethodsThis was a single-arm, open-label, interventional, post-authorization safety surveillance study of YAZ across 6 treatment cycles. Primary objective was assessing its safety profile in Chinese women. Secondary objectives included assessing contraceptive efficacy, cycle control, and bleeding patterns among subjects with and without preceding abortion, along with efficacy in moderate acne vulgaris. Subgroup ...
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
AbstractAndrogenetic alopecia (AGA) and acne vulgaris are two conditions commonly seen by dermatologists. Androgens and the androgen receptors play an essential role in the manifestation of both conditions, and some systemic therapies function by interfering in this pathway. The use of topical antiandrogen therapies has gained traction in recent years due to their potential efficacy in treating AGA and acne vulgaris, as well as their reduced adverse effects compared with systemic drugs. This review discusses the role of androgens in skin physiology and pathology and assesses the potential efficacy and safety of three topic...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
Cannabidiol (CBD) oil and other products containing CBD are being touted as a natural, organic remedy for a wide range of women’s health concerns. Sellers of these products make many claims: CBD has calming effects on sleep, mood, and anxiety; eases hot flashes and improves bone density by balancing hormonal changes of menopause; and has anti-inflammatory properties that clear skin, cure acne, and calm rosacea. It’s promoted for PMS symptoms like bloating and mood swings. And CBD-infused lubricants claim to boost arousal and enjoyment of sex. So, how much of this is true? First, what is CBD? CBD is a major ingr...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Complementary and alternative medicine Drugs and Supplements Health Marijuana Women's Health Source Type: blogs
Publication date: Available online 13 November 2019Source: Clinica Chimica ActaAuthor(s): Xin Zeng, Yuan-jie Xie, Ya-ting Liu, Shuang-lian Long, Zhong-cheng MoAbstractPolycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic abnormalities, including insulin resistance, excessive weight or obesity, type II diabetes, dyslipidemia and an increased risk of cardiovascular disease. The most significant clinical manifestation of PCOS is hyperandrogenism. Excess androgen profoundly affects granulosa cell function and...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Abstract Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic abnormalities, including insulin resistance, excessive weight or obesity, type II diabetes, dyslipidemia and an increased risk of cardiovascular disease. The most significant clinical manifestation of PCOS is hyperandrogenism. Excess androgen profoundly affects granulosa cell function and follicular development via complex mechanisms that lead to obesity and insulin resistance. Most PCOS patients with hyperandrogenism have steroid sec...
Source: International Journal of Clinical Chemistry - Category: Chemistry Authors: Tags: Clin Chim Acta Source Type: research
Publication date: Available online 8 November 2019Source: Reproductive ToxicologyAuthor(s): Nis Brix, Lea L.B. Lauridsen, Andreas Ernst, Jørn Olsen, Tine B. Henriksen, Cecilia H. Ramlau-HansenAbstractWe explored whether maternal alcohol intake in early pregnancy is associated with pubertal timing in sons and daughters. In total, 15,819 children, born 2000–2003 within the Danish National Birth Cohort, gave half-yearly, self-reported information on pubertal development (Tanner stages, voice break, first ejaculation, menarche, acne, and axillary hair) from 11 years during 2012–2018. Information on maternal ...
Source: Reproductive Toxicology - Category: Toxicology Source Type: research
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