Extracorporeal photopheresis for the treatment of graft rejection in 33 adult kidney transplant recipients

Background - Extracorporeal photopheresis (ECP) has shown encouraging results in the prevention of allograft rejection in heart transplantation. However, the role of ECP in kidney transplant (KT) rejection needs to be determined.Methods - This multicentre retrospective study included 33 KT recipients who were treated with ECP for allograft rejection (23 acute antibody-mediated rejections (AMRs), 2 chronic AMRs and 8 acute cellular rejections (ACRs)). The ECP indications were KT rejection in patients who were resistant to standard therapies (n  = 18) or in patients for whom standard therapies were contraindicated because of concomitant infections or cancers (n = 15).

Source: Transfusion and Apheresis Science - July 21, 2019 Category: Hematology Authors: Mathilde Tamain, Johnny Sayegh, Arnaud Lionet, Philippe Grimbert, Carole Philipponnet, Marc Hazzan, Jean-Fran çois Augusto, Mathias Büchler, Etienne Merlin, George Kosmadakis, Aurélien Tiple, Bruno Pereira, Cyril Garrouste, Anne-Elisabeth Heng Source Type: research