Repurposing Approved Drugs as Inhibitors of K v 7.1 and Na v 1.8 to Treat Pitt Hopkins Syndrome

ConclusionsThis work could lead to the potential repurposing of nicardipine or other dihydropyridine calcium channel antagonists as potential treatments for PTHS acting via Nav1.8, as there are currently no approved treatments for this rare disorder.

http://link.springer.com/10.1007/s11095-019-2671-y

Source: Pharmaceutical Research - July 21, 2019 Category: Drugs & Pharmacology Source Type: research