Reliving 25 years of Experience with Omeprazole in Acid-peptic Diseases.

Conclusion: Twenty five years after the introduction of omeprazole, the first of the PPIs, omeprazole has still remained a valuable drug in the armamentarium of clinicians. PMID: 31324090 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research

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In the early 1990s, doctors began describing a new condition affecting the esophagus of patients who were predisposed to allergies including food allergy, asthma, and eczema, and who were having trouble swallowing. Today, we call this condition eosinophilic esophagitis (EoE). What is EoE? EoE is an allergic inflammation of the esophagus that causes a range of symptoms. Adolescents and adults most often experience it as difficulty swallowing, sometimes feeling like food moves too slowly through the esophagus and into the stomach. In some cases, food actually gets stuck (and may require urgent removal). Children and some adu...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Allergies Digestive Disorders Health Source Type: blogs
ConclusionsHospitalization missed the opportunity to improve the quality of prescription of this class of drug.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research
Authors: Chen C, Gong X, Yang X, Shang X, Du Q, Liao Q, Xie R, Chen Y, Xu J Abstract Estrogen is an important sex steroid hormone which serves an important role in the regulation of a number of biological functions, including regulating bone density, brain function, cholesterol mobilization, electrolyte balance, skin physiology, the cardiovascular system, the central nervous system and female reproductive organs. Estrogen exhibits various functions through binding to its specific receptors, estrogen receptor α, estrogen receptor β and G protein-coupled estrogen receptor 1. In recent years, researchers ha...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
r N Abstract PURPOSE: To test whether Schirmer test (ST) results are associated with topical or systemic medication and to evaluate the distribution of tear fluid quantity in a 3-min and 5-min ST. METHODS: The Gutenberg Health Study is a population-based, prospective, observational cohort study in Germany. ST was assessed in a sub-cohort of 1,999 participants. ST was performed under topical anesthesia for 5 min (ST-5) or of 3 min (ST-3). Anthropometric factors, systemic diseases, use of systemic and eye medications were recorded. We used multivariable quantile regression analysis to assess the influence o...
Source: The Ocular Surface - Category: Opthalmology Authors: Tags: Ocul Surf Source Type: research
Publication date: Available online 17 September 2019Source: Best Practice &Research Clinical GastroenterologyAuthor(s): Serhat BorAbstractThe pathogenesis of gastroesophageal reflux disease has been explained by acid-peptic model. However, related with the progress of the diagnostic modalities, another phenotypical group of patients were defined and called “functional disorders of the esophagus”. These patients are important because diagnosis is particularly difficult, co-morbid disorders especially psychiatric diseases are common, proton pump inhibitor response is low, and surgical results are very poor. S...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
Publication date: Available online 17 September 2019Source: Best Practice &Research Clinical GastroenterologyAuthor(s): Serhat BorABSTRACT:The pathogenesis of gastroesophageal reflux disease has been explained by acid-peptic model. However, related with the progress of the diagnostic modalities, another phenotypical group of patients were defined and called “functional disorders of the esophagus”. These patients are important because diagnosis is particularly difficult, co-morbid disorders especially psychiatric diseases are common, proton pump inhibitor response is low, and surgical results are very poor. ...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
An 82-year-old male, with a history of bowel cancer with partial colectomy, gastroesophageal reflux disease, remote partial gastrectomy for peptic ulcer disease, and no documented prior kidney disease, presents with several months of fatigue and subacute decline in kidney function. He had no history of diabetes, hypertension, kidney stones, or prior urinary tract infections. He denied use of nonsteroidal anti-inflammatory agents, herbal medications, and recent antibiotics. There was no family history of renal disease.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Make Your Diagnosis Source Type: research
Authors: Mohammadifard M, Saremi Z, Rastgoo M, Akbari E Abstract There is evidence that infection by H. pylori can have a critical proportion in the development of hepatocyte injury and both noncancerous and malignant liver conditions including non-alcoholic fatty liver disease (NAFLD). This is attributed to several mechanisms, the most important one being the toxic products of the bacterium H. pylori and oxidative injury for hepatocytes which promotes hepatic injury. The present research was aimed at determining the association between H. pylori infection and the prevalence of NAFLD in Birjand, Iran. Two groups we...
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research
Background and Aims: Proton pump inhibitors (PPIs) such as omeprazole are gastric acid-suppressing agents that are used to treat gastroesophageal reflux disease and peptic ulcers. In contrast, PPIs are also associated with gut microbiota dysbiosis and increased cardiovascular disease risk. However, proof of a causal link between PPI use, dysbiosis and cardiovascular disease is missing.
Source: Atherosclerosis - Category: Cardiology Authors: Tags: E-poster session Source Type: research
Pantoprazole is a drug that can help treat conditions such as acid reflux and peptic ulcers. We look at pantoprazole ’s uses, dosage, and side effects, and what to know before taking it.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Acid Reflux / GERD Source Type: news
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