Antimicrobial resistance of Pasteurella multocida isolated from diseased food-producing animals and pets

Publication date: Available online 21 July 2019Source: Veterinary MicrobiologyAuthor(s): Clémence Bourély, Géraldine Cazeau, Eric Jouy, Marisa Haenni, Jean-Yves Madec, Nathalie Jarrige, Agnès Leblond, Emilie GayAbstractSurveillance of Pasteurella multocida resistance in food-producing animals is essential to guide the first-line treatment of respiratory diseases and to limit economic losses. Since Pasteurella are the most common bacteria isolated from dog and cat bites, this surveillance is also needed to guide treatment in humans in case of bites. The aim of this study was to characterize the phenotypic resistance of P. multocida strains isolated from respiratory infections in animals, including both food-producing animals and pets. Data collected between 2012 and 2017 by the French national surveillance network for antimicrobial resistance referred to as RESAPATH were analyzed. The proportions of resistance to antimicrobials of relevance in veterinary and human medicines were estimated for each animal species. For cattle, resistance trends over the period were investigated using non-linear analysis applied to time-series. In total, 5,356 P. multocida isolates were analyzed. Proportions of resistance of P. multocida were almost all below 20% over the period, and, more precisely, all resistance proportions were below 10% for rabbits, sheep and dogs. The highest resistance proportions to enrofloxacin were identified for cattle (4.5%) and dogs (5.2%). Despite its frequent u...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research