Peripartum Cardiomyopathy: a Review

This article conducts a review of recent literature and gives insight into this disease.Recent FindingsThere is promising research in the fields of vascular, hormonal, and genetics. A number of genetic markers are being analyzed, including TTNC1, TTN, and STAT3. Mutations to these genes have been found to be prevalent in PPCM. These combined with the secretion of placental angiogenic factors potentially create imbalance in angiogenesis as the primary etiology.SummaryCurrent biomarkers do not differentiate between PPCM and other variants of heart failure. Women with PPCM are more likely to have a cesarean section, to have hypertensive disease, at greater risk of major adverse cardiac events, and to have lifelong morbidity.

Source: Current Emergency and Hospital Medicine Reports - July 21, 2019 Category: Emergency Medicine Source Type: research