TWiV 557: Congress in Rotterdam

From the European Congress of Virology in Rotterdam, Vincent and local co-host Ben Berkhout speak with Ron Fouchier, Rosina Girones, and Marie-Paule Kieny about their careers and their work on influenza virus, environmental virology, and developing an Ebola virus vaccine during an epidemic. Click arrow to play Download TWiV 557 (41 MB .mp3, 67 min) Subscribe (free): iTunes, Google […]
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology antigenic drift ebola virus environmental virology epidemic global health H2N2 influenza virus pandemic vaccine viral viruses viruses in water Source Type: blogs

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Publication date: Available online 25 August 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Huseyin Bilgin Bilgic, Selin Hacilarlioglu, Serkan Bakirci, Onur Kose, Ahmet Hakan Unlu, Ayca Aksulu, Metin Pekagirbas, Jabbar Ahmed, Christina Deschermeier, Gordon Langley, Tulin KaragencAbstractBabesiosis is a disease complex caused by unicellular Babesia parasites and among them, malignant ovine babesiosis caused by B. ovis has a devastating economical impact on the small ruminant industry. The control of disease is mainly based on chemotherapy and preventing animals from tick infestation and to date no vaccine is available ...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
The objectives of this retrospective study were to identify the prevalence and distribution of M. ovis, and identify associated demographic and management risk factors, and reproductive and production outcomes associated with infection on domestic sheep (Ovis aries) operations in the United States. As part of the United States Department of Agriculture (USDA), Animal Plant Health Inspection Service, Veterinary Services’ National Animal Health Monitoring System (NAHMS) Sheep 2001 and 2011 studies, blood was collected and sera banked from 21,369 ewes in 2001 and 13,128 ewes in 2011. Participating premises were located ...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Publication date: Available online 24 August 2019Source: Journal of BiotechnologyAuthor(s): Kiran Saba, Johanna Gottschamel, Iqra Younus, Tahira Syed, Kehkshan Gull, Andreas Günter Lössl, Bushra Mirza, Mohammad Tahir WaheedAbstractMycobacterium tuberculosis causes tuberculosis in humans. The major disease burden of tuberculosis lies in developing countries. Lack of an effective vaccine for adults is one of the major hurdles for controlling this deadly disease. In the present study, 6 kDa early secretory antigenic target (ESAT-6) of M. tuberculosis was inducibly expressed in chloroplasts of Nicotiana tabacu...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 23 August 2019Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Stuti Bhagat, Yashvi Parikh, Sanjay Singh, Souvik SenguptaAbstractLeishmaniasis is a notorious disease affecting mainly poor people. Visceral Leishmaniasis (VL) is a clinical form of Leishmaniasis which mainly affects people living below poverty line. There are no available vaccines against VL and chemotherapy still remains the mainstay for treatment. However, the use of the current therapeutic agents are limited due to issues of toxicity, side effects and cost effectiveness. Thus, repositioni...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
Oklahoma to decide whether healthcare company contributed to deadly epidemic
Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news
[New Times] Global experts are going to share research on HIV vaccines and cures in a meeting that will bring together over ten thousand delegates in Kigali in December.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
Publication date: Available online 23 August 2019Source: BiologicalsAuthor(s): Silvio Bandiera, Annabelle Lebas, Livia Canizares-Martinello, Fabien Guinchard, Corinne Lyonnais, Sophie Perrin, Marine Nicolas, Sylvie Uhlrich, Martine Chabaud-RiouAbstractThe diphtheria toxoid (DT), tetanus toxoid (TT), and acellular pertussis (aP) single immunogenicity assay (DTaP SIA) is a Luminex®-xMAP®-bead-based multiplex immunoassay for estimating the potency of DTaP pediatric combination vaccines in guinea pigs. This manuscript describes the validation of this assay for the simultaneous quantitation of anti-diphtheria toxoid (an...
Source: Biologicals - Category: Biology Source Type: research
Publication date: Available online 23 August 2019Source: Biochemical Engineering JournalAuthor(s): Vanessa Zavatti, Hector Budman, Raymond L. Legge, Melih TamerAbstractThe response of Bordetella pertussis to induced oxidative stress during fermentation was assessed. B. pertussis is the causal agent of whooping cough in humans and purified pertactin (PRN) is used as one of the components in the production of acellular pertussis vaccines. When grown in bioreactors, bacteria adapt to environmental conditions which may include high levels of reactive oxidative species (ROS) that stress cells and can have detrimental effects on...
Source: Biochemical Engineering Journal - Category: Biochemistry Source Type: research
oguslaw Szewczyk Newcastle disease (ND) is responsible for significant economic losses in the poultry industry. The disease is caused by virulent strains of Avian avulavirus 1 (AAvV-1), a species within the family Paramyxoviridae. We developed a recombinant construct based on the herpesvirus of turkeys (HVT) as a vector expressing two genes: F and HN (HVT-NDV-F-HN) derived from the AAvV-1 genotype VI (“pigeon variant” of AAvV-1). This recombinant viral vaccine candidate was used to subcutaneously immunize one group of specific pathogen-free (SPF) chickens and two groups of broiler chickens (20 one-d...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
CONCLUSIONS: Genomic analysis of three recent ZIKV isolates revealed some nonsynonymous substitutions, which could have an impact on the viral fitness in mammalian and insect cells. PMID: 31432892 [PubMed - in process]
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Tags: Mem Inst Oswaldo Cruz Source Type: research
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