Antiphospholipid antibodies in Buerger's disease

Buerger's disease (BD), or thromboangiitis obliterans, is an inflammatory, occlusive, peripheral vascular disease which usually occurs in young male smokers from low- or middle-income countries. The occlusion of small and medium-sized arteries may lead to tissue or limb loss. The aetiology and pathophysiology of the disease is not well understood. Although there is a close relationship between smoking and development or prognosis of the disease, smoking on its own cannot explain the low prevalence and geographical distribution of BD [1].
Source: Thrombosis Research - Category: Hematology Authors: Tags: Letter to the Editors-in-Chief Source Type: research