Is economic status the main determinant of radiation therapy availability? The Arab world as an example of developing countries.
CONCLUSION: Although the economic status is of paramount importance, it is not the only factor determining the quantity and quality of radiotherapy services in the Arab world. More efforts are urgently needed to improve the status of radiation oncology and fill its gap in the Arab countries. PMID: 31323472 [PubMed - as supplied by publisher]
Hepatocellular carcinoma (HCC) is one of the quickest growing causes of cancer death in the northern hemisphere. Transplant and resection, the only treatments considered curative, are feasible in only a small minority of patients. Consequently, the landscape of HCC treatment has greatly expanded over the past 10 years. Patients are undergoing treatment with a wide variety of nonoperative interventions, including transarterial chemoembolization and radioembolization using Yttrium-90, and an expanding array of systemic treatments, including sorafenib, regorafenib, and nivolumab.
We read with interest the article published by Palma et al reporting a phase 2 clinical trial of preoperative stereotactic ablative radiation therapy (SABR) plus surgery in patients with early stage non-small cell lung cancer (NSCLC).1 Surgery was implemented in 10 weeks after SABR. The authors concluded that the pathologic complete response (pCR) rate after SABR was 60%, which was lower than the hypothesized 90% pCR rate. Preoperative SABR and surgery combination did not increase toxicity more than surgery alone, and there was no perioperative mortality.
Cancer of the true glottis has a very low rate of regional metastasis; thus, curative treatment depends on optimized local therapy, with disease-free survival rates in excess of 90%.1 For radiation therapy, the challenge has been enhancing efficacy while preserving or improving the late toxicity of treatment, including effects on voice quality and laryngeal function. As context, hypofractionated radiation therapy (2.25 Gy daily) has been shown to improve local control for early stage glottic cancer compared with daily 2 Gy regimens, with acceptable toxicity of ∼15% to 20% late grade 1 skin or laryngeal effects.
External beam radiation therapy (RT) is currently a standard of care for early stage (T1-T2) glottic cancer, but it is being gradually supplanted by surgical approaches; endoscopic, laser, and robotic techniques allow less invasive access to glottic tumors, despite some evidence of worse oncologic outcomes.1 Surgical excision is often chosen, likely because of the increased convenience of a single outpatient procedure compared with several weeks of daily radiation treatments and the benefit of avoiding substantial radiation exposure to the normal tissues surrounding the larynx with standard 2-dimensional techniques, which ...
ConclusionsThe radiation oncologist numbers have increased significantly, but unemployment remains low. Many parameters remain similar to the 2014 census, but new information has been obtained on special interest areas, leadership positions, gynae ‐oncology, inpatients, hypofractionation use, remuneration and contouring. Trainee numbers remain stable with an increased percentage satisfied with their career with much less concern about oversupply. Protected time remains an issue with contouring time and teaching emerging as a potential issue .
o Jin-Min Nam Radiotherapy is used extensively in cancer treatment, but radioresistance and the metastatic potential of cancer cells that survive radiation remain critical issues. There is a need for novel treatments to improve radiotherapy. Here, we evaluated the therapeutic benefit of λ-carrageenan (CGN) to enhance the efficacy of radiation treatment and investigated the underlying molecular mechanism. CGN treatment decreased viability in irradiated cancer cells and enhanced reactive oxygen species accumulation, apoptosis, and polyploid formation. Additionally, CGN suppressed radiation-induced chemoinvas...
Conclusion: VMAT combined with IC/IS BT can result in satisfactory curative outcomes and low incidences of late radiation enterocolitis and cystitis in CC treatment.
Conditions: Non Small Cell Lung Cancer; Brain Metastases Interventions: Drug: Icotinib; Radiation: SRS/WBRT/HA-WBRT/SMART Sponsor: Betta Pharmaceuticals Co., Ltd. Recruiting
SOMATOM Definition Flash, Model Number 10430603 - Product Usage: Computed tomography systems intended to generate and process cross-sectional images of patients by computer reconstruction of x-ray transmission data. The images delivered by the system can be used by a trained physician as an aid in diagnosis. The images delivered by the system can be used by trained staff as an aid in diagnosis, treatment preparation and radiation therapy planning. These CT systems can be used for low dose lunch cancer screening in high risk populations (as defined by professional medical societies).