Which Window Setting Is Best for Estimating Pathologic Invasive Size and Invasiveness?

Publication date: August 2019Source: The Annals of Thoracic Surgery, Volume 108, Issue 2Author(s): Joji Samejima, Hiroyuki Ito, Haruhiko Nakayama, Takuya Nagashima, Junichiro Osawa, Kenji Inafuku, Masaki Suzuki, Tomoyuki Yokose, Kouzo Yamada, Munetaka MasudaBackgroundIn the Eighth Edition of the Tumor Node Metastasis Classification System for Lung Cancer, the definitions of the clinical T and pathologic T descriptors have changed. Little has been reported on comparisons between the consolidation diameter in the lung window setting and the tumor diameter in the mediastinal window setting with respect to the correlations with pathologic invasive size (IS) and invasiveness. The present study was conducted to clarify which window setting was better for preoperatively estimating IS and invasiveness.MethodsWe retrospectively reviewed 1,167 consecutive patients with lung adenocarcinomas measuring 3 cm or less in diameter. We measured three high-resolution computed tomography variables and examined correlations of IS with these variables, factors predictive of an IS of 5 mm or less, and other variables related to invasiveness.ResultsOn receiver operating characteristic curve analysis, the tumor diameter in the mediastinal window setting more strongly predicted IS than did the consolidation diameter in the lung window setting (p
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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