Physician-Modified Thoracic Stent Grafts for the Arch After Surgical Treatment of Type A Dissection
ConclusionsThe use of physician-modified thoracic stent grafts for the treatment of dissecting aortic arch aneurysm after surgical treatment of acute type A dissection is feasible and effective. Durability concerns will need to be assessed in future studies.Visual Abstract
ConclusionsIn SR patients with CAD and HF, the rates of MI and stroke associated with rivaroxaban combined with APT were lower than those associated with APT alone, and the two treatments had similar rates of all-cause death and major bleeding.
ConclusionsThere were no demonstrable treatment differences across SGLT2 inhibitors across cardiovascular, renal, and metabolic outcomes, although this needs to be interpreted considering the wide confidence intervals, limited number of included studies, and heterogeneity present. Future research of different SGLT2 inhibitors in head-to-head studies is warranted to determine if there is a drug class effect.
STROKE remains one of the leading causes and death and disability worldwide, yet little can be done to prevent an incident. Changing one's lifestyle habits can, however, curtail the likelihood of an incident. How often you nap could determine your risk of the life-threatening condition.
When treating a person who's suffered a stroke, it matters a lot what kind of stroke it was. It's particularly important to know whether the stroke was caused by a blood clot in one of the large arteries leading to the brain. That's because that type of stroke, known as a large vessel occlusion, needs to be treated right away, but not every hospital is equipped to provide the necessary tr eatment. Unfortunately, with the equipment they typically have, first responders generally can't tell whether…
AbstractNoscapine has been mentioned as one of the effective drugs with potential therapeutic applications. With few side effects and amazing capabilities, noscapine can be considered different from other opioids-like structure compounds. Since 1930, extensive studies have been conducted in the field of pharmacological treatments from against malaria to control cough and cancer treatment. Furthermore, recent studies have shown that noscapine and some analogues, like 9-bromonoscapine, amino noscapine, and 9-nitronoscapine, can be used to treat polycystic ovaries syndrome, stroke, and other diseases. Given the numerous resul...
Conditions: Brain Edema; TBI (Traumatic Brain Injury); Stroke, Acute; Cerebral Hemorrhage; Brain Tumor Interventions: Procedure: Dynamic craniotomy; Device: Dynamic craniotomy Sponsors: Rohit Khanna, MD; Halifax Health Not yet recruiting
Conditions: Ischemic Stroke, Acute; Thrombectomy; Anesthesia, General; Cerebrovascular Circulation; Carbon Dioxide Interventions: Biological: HYPERCAPNIA; Biological: NORMOCAPNIA Sponsor: University Hospital, Clermont-Ferrand Not yet recruiting
Condition: Stroke Intervention: Sponsor: Herlev Hospital Not yet recruiting
AbstractAimsRheumatic heart disease (RHD) remains a major global health problem. Renin –angiotensin–aldosterone system inhibitors (RAASi) are commonly administered in the treatment of cardiovascular disease, but its role in RHD patients is still limited. We performed a retrospective study to determine the effect of RAASi on long-term outcomes for RHD patients.Methods and resultsA 1:1 propensity score matching was implemented to balance baseline characteristics between groups RAASi and non-RAASi. Cox proportional hazards regression model was used to investigate the associations of RAASi with the risks of all-cau...
This study is aimed at determining the impact of serum holoTC level as a risk factor for ischemic stroke and investigating its association with disease severity and short-term outcomes.METHODS: Serum holoTC, total B12, and homocysteine levels were compared between 130 stroke patients and 138 healthy controls. Biomarker level correlations with disease severity and stroke functional outcomes were investigated.RESULTS: holoTC levels were lower and homocysteine levels were higher in stroke patients than in healthy controls (P