Development of oligonucleotide microarray for accurate and simultaneous detection of avian respiratory viral diseases

Avian influenza virus (AIV), infectious bronchitis virus (IBV), and Newcastle disease virus (NDV) are important avian pathogens that can cause enormous economic loss on the poultry industry. Different respirat...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Methodology article Source Type: research

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CONCLUSION: This research suggests that studies of pathogenic viromes in different diseases can help monitor different diseases and predict their future occurrence.PMID:34540172 | PMC:PMC8416587 | DOI:10.18502/ijm.v13i3.6396
Source: Iranian Journal of Microbiology - Category: Microbiology Authors: Source Type: research
Biol Trace Elem Res. 2021 Aug 20. doi: 10.1007/s12011-021-02885-x. Online ahead of print.ABSTRACTSeveral studies have been conducted to assess the effects of supplemental dietary chromium (Cr) on broiler chickens under heat stress (HS) conditions, but the shape and strength of the associations between Cr supplementation and broiler chickens' responses to HS remain unclear. Therefore, the current systematic review and meta-analysis investigated the effectiveness and dose-response relationship of Cr. The results indicated non-linear dose-response associations between Cr supplementation and body mass gain (BMG), feed intake (...
Source: Biological Trace Element Research - Category: Biology Authors: Source Type: research
Anim Biotechnol. 2021 Jul 19:1-6. doi: 10.1080/10495398.2021.1950744. Online ahead of print.ABSTRACTThe effect of in ovo feeding of different levels of vitamins C and E on egg hatchability, immune response, growth and carcass traits of broiler chickens were investigated. A total of 672 fertilized eggs were assigned to one of eight experimental groups having three replicates with 28 eggs as follows: (1) negative control (not injected); (2) positive control (injected with 0.2 mL deionized water); (3) vitamin C at 1 mg; (4) vitamin C at 3 mg; (5) vitamin C at 6 mg; (6) vitamin E at 0.5 IU; (7) vitamin E at 0.75 IU; and (8) vi...
Source: Animal Biotechnology - Category: Biotechnology Authors: Source Type: research
Avian Pathol. 2021 Apr 7:1-20. doi: 10.1080/03079457.2021.1912287. Online ahead of print.ABSTRACTSUMMARYAn unusual case of Infectious Bursal Disease (IBD) was observed in eight-week-old commercial caged pullets. This flock (House 1) exhibited a one-day spike in mortality. On gross necropsy examination, enlarged, diffusely hemorrhagic bursas were observed. This lesion has been frequently described in cases of very virulent Infectious Bursal Disease Virus (vvIBDV). A five-week-old caged pullet flock (House 2) in an adjacent building did not display hemorrhagic bursa lesions. Microscopic examination of bursas from the eight-w...
Source: Avian Pathology - Category: Pathology Authors: Source Type: research
Virus Res. 2021 Mar 8:198383. doi: 10.1016/j.virusres.2021.198383. Online ahead of print.ABSTRACTSlightly acidic hypochlorous acid waters (SAHWs) with pH of 5.2-5.8 containing different concentrations of free available chlorine - 62, 119, 220, 300, and 540 ppm (SAHW-62, -119, -220, -300, and -540, respectively) - were evaluated for their virucidal activity toward a low pathogenic H7N1 avian influenza virus (AIV) and an infectious bronchitis virus (IBV) in suspension, abiotic carrier, and direct spray tests, with the presence of organic materials. In the carrier test, the dropping and wiping techniques were performed toward...
Source: Virus Research - Category: Virology Authors: Source Type: research
In this study, a novel triplex protein microarray assay was developed and validated for the rapid and simultaneous visualized detection of antibodies against AIV, NDV, and IBV in chicken sera. The AIV nuclear protein (NP), NDV phosphoprotein (P), and IBV nonstructural protein 5 (nsp5) were produced in a prokaryotic expression system, purified, and immobilized onto an initiator integrated poly(dimethylsiloxane) (iPDMS) film as probes to detect antibodies against these viruses in chicken sera. After optimization of the reaction conditions, no cross-reactivity was detected with infectious bursal disease virus, avian leukosis ...
Source: Archives of Virology - Category: Virology Source Type: research
             Basel, 24 November 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) for Xofluza ® (baloxavir marboxil) as a treatment to prevent influenza in people 12 years of age and older following contact with someone with influenza (known as post-exposure prophylaxis). Xofluza is the first single-dose influenza medicine approved for post-exposure prophylaxis.“With today’s approval, Xofluza is now available as the first single-dos...
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
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