Targeted Therapies: Treatment Options for Patients With Metastatic Breast Cancer.

This article reviews targeted therapy treatment options for patients with metastatic BC, including strategies for administration, side effects, and nursing considerations. PMID: 31322617 [PubMed - in process]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Clin J Oncol Nurs Source Type: research

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Publication date: December 2019Source: Materials Science and Engineering: C, Volume 105Author(s): Mohamed Gaber, Mark Hany, Sarah Mokhtar, Maged W. Helmy, Kadria A. Elkodairy, Ahmed O. ElzoghbyAbstractMulti-modality strategies of albumin-mediated drug accumulation in tumor, boronate-based active tumor targeting and synergistic cancer therapy were combined together for effective treatment of breast cancer. Herein we report the development of albumin-shell oily-core nanocapsules (NCs), loaded with novel combination of hydrophobic drugs, exemestane (EXE) and hesperetin (HES), for targeted breast cancer therapy. This protein-l...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Conclusions. The BENECA mHealth lifestyle application with a supervised rehabilitation program had a statistically and clinically significant effect on QoL and upper-limb functionality in breast cancer survivors and is a unique and important promising new approach.
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: 5 January 2020Source: Journal of Molecular Structure, Volume 1199Author(s): Di Wu, Liang Guo, Si-Jie LiAbstractTwo Schiff base ligands 2-((ethylamino)methyl)-6-methoxyphenol (HL1) and (E)-2-(((2-(dimethylamino)ethyl)imino)methyl)-6-methoxyphenol (HL2) with bi-nucleating or tri-nucleating mode have been successfully prepared via an one step organic condensation reaction, which were further applied in the synthesis of three new Cu(II) and Ni(II)-based coordination complexes [Cu(L1)2](EtOH) (1), [Ni(L1)2](EtOH) (2) and [Cu(L2)(HL2)(SCN)](MeOH)2 (3). Furthermore, a hand grinding technique has been used to dec...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 23 August 2019Source: Journal of Photochemistry and Photobiology A: ChemistryAuthor(s): Gonzalo Ramírez-García, Miguel Ángel Honorato-Colin, Elder De la Rosa, Tzarara López-Luke, Sandeep S. Panikar, José de Jesús Ibarra-Sánchez, Valeria PiazzaAbstractThe multifunctional hybrid nanomaterials could bring alternative solutions to current public health problems like cancer diagnosis and treatment. In this work, the near-infrared-activated NaYF4:Yb,Er up-conversion nanoparticles (UCNPs) were synthesized and covalently decorated with sub-10&thins...
Source: Journal of Photochemistry and Photobiology A: Chemistry - Category: Chemistry Source Type: research
In this study, we developed a nucleus-targeting nanoparticle system for combining PTT/PDT and chemotherapy to treat breast cancer. IR780, a near-infrared (NIR) fluorescence dye that has potent anticancer efficacy of PTT and PDT, was firstly conjugated with TAT peptide through substitution reaction between chlorine atom and sulfhydryl group, thus obtained a conjugate TAT-IR780 with notably enhanced water solubility and optical stability. Next, chemotherapeutic drug doxorubicin (DOX) and TAT-IR780 self-assembled in aqueous medium to form TID nanoparticles with a small size of approximately 100 nm. Both in vitro and in vivo...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Publication date: 24 August 2019Source: New Scientist, Volume 243, Issue 3244Author(s): Clare Wilson
Source: New Scientist - Category: Science Source Type: research
Conclusions: The study documented the low level of BC knowledge among male partners. There is an urgent need to pay more consideration to disseminating awareness among men, as they are associates, and they must be armed with proper awareness. There is an urgent demand for establishing a national program and educational campaigns towards BC. Stressing the advantages and access to free mammography is necessary.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
The objective of this article is to document whether DIRT can accurately map the position of the perforators and measure their influence on the perfusion of the flap in order to select the best perforators to improve the outcome of breast reconstructions with free DIEP flaps. A systematic review of the literature published between January 1998 and November 23th 2018 was conducted regarding the possible benefit of dynamic infrared thermography (DIRT) in DIEP-flap breast reconstructions.The databases PubMed and Web of Science were used to search for qualified articles. Inclusion criteria were women who underwent a breast rec...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Alpelisib (Piqray) is now approved to treat postmenopausal women or men who have hormone receptor–positive, human epidermal growth factor receptor 2–negative, PIK3CA-mutated, advanced or metastatic breast cancer that has progressed during or after endocrine-based therapy.
Source: AJN - Category: Nursing Tags: Drug Watch Source Type: research
Authors: Emens LA PMID: 31437135 [PubMed - in process]
Source: Clinical Advances in Hematology and Oncology - Category: Cancer & Oncology Tags: Clin Adv Hematol Oncol Source Type: research
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