Histological study of intestinal goblet cells, IgA, and CD 3+ lymphocyte distribution in Huang-huai white goat.

Histological study of intestinal goblet cells, IgA, and CD 3+ lymphocyte distribution in Huang-huai white goat. Folia Morphol (Warsz). 2019 Jul 19;: Authors: Zhou J, Zhang W, Liu W, Sheng J, Li M, Chen X, Dong R Abstract Ten healthy adult Huang-huai white goats were selected and sacrificed by jugular vein bleeding after anesthesia to observe the distribution characteristics of the histological structure of the intestinal mucosa, goblet cells, IgA, and CD 3+ lymphocytes. Three sections of the duodenum, the jejunum, and the ileum were immediately collected and fixed with 4% paraformaldehyde for 72 h to prepare tissue sections. After HE, PAS, and immunohistochemical staining was performed, the distribution characteristics of goblet cells, IgA-positive cells, and CD 3+ lymphocytes were observed. Results showed high columnar epithelial cells in the duodenum and jejunum of Huang-huai white goat and low columnar epithelial cells in the ileum mucosa. Mucopolysaccharides secreted by intestinal goblet cells were mainly neutral, and the number of ileum goblet cells was significantly higher than that of the duodenum and the jejunum (P<0.05). IgA-positive cells were distributed in the lamina propria of the duodenum, and the number of cells was significantly higher than that in the jejunum and the ileum (P<0.01). The significant difference was found between the jejunum and the ileum (P<0.01). The CD3+ cells in the intestinal mucosa were d...
Source: Folia Morphologica - Category: Anatomy Tags: Folia Morphol (Warsz) Source Type: research