Antioxidant and antimicrobial investigations of Elaeocarpus tectorius (lour.) poir. Fruits against urinary tract infection pathogens.

Publication date: Available online 20 July 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Ashwini Lydia Manoharan, Suman Thamburaj, Kasipandi Muniyandi, Gayathri Jagadeesan, Saikumar Sathyanarayanan, Gayathri Nataraj, Parimelazhagan ThangarajAbstractPlants are the natural honorarium used for primary health care and people rely upon herbal medications for the prevention and cure of numerous diseases that are caused by infectious pathogens. The extracts of Elaeocarpus tectorius fruits were successively prepared using five solvents (Petroleum ether, Dichloromethane, Ethyl acetate, Methanol and water) varying in their polarity ranges. The fruits of E. tectorius were screened for phytoconstituents such as alkaloids, flavonoids, terpenoids, steroids, glycosides that are endowed for the free radical scavenging activity. Fruit extracts showed significant amount of phenolics in ethyl acetate extract (302.33 ± 46.06 mg GAE/g extract), tannins in methanol extract (60.53 ± 2.66 mg GAE/g extract) and flavonoids in water extract (239.30 ± 9.79 mg RE/g extract). Ethyl acetate extract was efficient showing maximum antioxidant activity with the lowest IC50 value in diphenyl-1-picrylhydrazyl radical-scavenging assay (20 μg/mL), ferric reducing/antioxidant power assay (3203.92 ± 413.62 mM (Fe(II)E/mg extract) and phosphomolybdenum assay (881.00 ± 28.51 mg AAE/g extract). Plants tend to express antimicrobial activity which are therefore tw...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research