X-ray dose delivered during a longitudinal micro-CT study has no adverse effect on cardiac and pulmonary tissue in C57BL/6 mice.

ConclusionThis study demonstrated that a 5 Gy X-ray dose accumulated over 6 weeks during a longitudinal micro-CT study had no significant effects on the pulmonary and myocardial tissue of C57BL/6 mice. As a result, the many advantages of micro-CT imaging, including rapid acquisition of high-resolution, isotropic images in free-breathing mice, can be taken advantage of in longitudinal studies without concern for negative dose-related effects. PMID: 23436828 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/PubMed/23436828?dopt=Abstract

Source: Acta Radiologica - February 23, 2013 Category: Radiology Authors: Detombe SA, Dunmore-Buyze J, Petrov IE, Drangova M Tags: Acta Radiol Source Type: research