Intermolecular interactions and permeability of 5-fluorouracil cocrystals with a series of isomeric hydroxybenzoic acids: a combined theoretical and experimental study

CrystEngComm, 2019, Accepted Manuscript DOI: 10.1039/C9CE00661C, PaperXia-Lin Dai, Alexander P. Voronin, Wei Gao, German L. Perlovich, Tong-Bu Lu, Jia-Mei Chen 5-Fluorouracil (5FU) is a BCS class III drug with good aqueous solubility and poor permeability, which severely limits its transdermal permeation through stratum corneum. Herein, four cocrystals of 5FU with... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - CrystEngComm latest articles - July 20, 2019 Category: Chemistry Authors: Xia-Lin Dai Source Type: research