Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea

Conditions:   Coronary Artery Disease;   Obstructive Sleep Apnea of Adult Interventions:   Other: OSA;   Other: Non-OSA Sponsor:   Beijing Anzhen Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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AbstractPurposeThe negative association between obstructive sleep apnea (OSA) and adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention (PCI) is well documented. However, little is known about the influence of OSA on fibrinolytic therapy. The aim of this study was to evaluate the impact of severe OSA on pharmacoinvasive treatment in ST elevation myocardial infarction (STEMI) patients.MethodsWe enrolled consecutive STEMI patients without previous vascular disease, heart failure, or OSA diagnosis. All patients underwent either a pharmacoinvasive therapy or primary PCI. Syntax score (SS) wa...
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
Abstract PURPOSE: The negative association between obstructive sleep apnea (OSA) and adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention (PCI) is well documented. However, little is known about the influence of OSA on fibrinolytic therapy. The aim of this study was to evaluate the impact of severe OSA on pharmacoinvasive treatment in ST elevation myocardial infarction (STEMI) patients. METHODS: We enrolled consecutive STEMI patients without previous vascular disease, heart failure, or OSA diagnosis. All patients underwent either a pharmacoinvasive therapy or primary PCI. ...
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
AbstractObstructive sleep apnea (OSA) is associated with coronary artery disease (CAD) and with an increased risk for myocardial infarction, stroke or death due to cardiovascular disease. Optical frequency-domain imaging (OFDI) is a useful modality for evaluating the characteristics of atherosclerotic plaque. The purpose of the study was to use OFDI to investigate the association of OSA with coronary plaque characteristics in patients undergoing percutaneous coronary intervention (PCI). We retrospectively analyzed OFDI data for coronary artery plaques from 15 patients with OSA and 35 non –OSA patients treated between...
Source: Heart and Vessels - Category: Cardiology Source Type: research
Publication date: Available online 5 March 2019Source: American Heart JournalAuthor(s): Matias B. Yudi, David J. Clark, Omar Farouque, Nick Andrianopoulos, Andrew E. Ajani, Angela Brennan, Jeffrey Lefkovits, Melanie Freeman, Chin Hiew, Laura A. Selkrig, Jessica O’Brien, Anthony M. Dart, Christopher M. Reid, Stephen J. Duffy, Melbourne Interventional GroupSTRUCTURED ABSTRACTBackgroundRepeat hospitalizations for recurrent acute coronary syndrome (ACS) or unplanned revascularization after acute myocardial infarction (MI) are common, costly and potentially preventable. We aim to describe 10-year trends and identify indep...
Source: American Heart Journal - Category: Cardiology Source Type: research
Conclusion: Nocturnal ACS events occur more frequently in patients with younger age, higher BMI and larger neck circumference. Patients with nocturnal ACS onset have a high likelihood of having OSA, thus should be prioritized for polysomnography.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and control of breathing Source Type: research
Conclusion: Patients with ACS and OSA (AHI≥15) seem to have better prognosis, according to parameters of myocardial damage. AHI
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and control of breathing Source Type: research
Study Objectives:Sleep apnea is often newly diagnosed in patients presenting with ST-segment elevation myocardial infarction (STEMI). We assessed longitudinal changes in apnea-hypopnea index (AHI) and sleep apnea phenotype after STEMI and determined its association with changes in the left ventricular ejection fraction (LVEF).Methods:A total of 101 eligible patients with STEMI underwent consecutive sleep studies and echocardiographic studies within 5 days of admission and at 6-month follow-up. Sleep apnea (AHI≥ 15 events/h) was further divided into obstructive sleep apnea (OSA) or central sleep apnea (CSA).Results:Both ...
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
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