Neuroinflammation in frontotemporal dementia

Nature Reviews Neurology, Published online: 19 July 2019; doi:10.1038/s41582-019-0231-zAn altered microglial landscape and ageing-related inflammatory changes contribute to the neurodegeneration associated with frontotemporal dementia (FTD). Here, Bright and colleagues discuss the evidence for a pathogenetic role of neuroinflammatory mechanisms in FTD, including links with autoimmunity and gene mutations associated with neuroinflammation.

Source: Nature Reviews Neurology - July 18, 2019 Category: Neurology Authors: Fiona Bright Eryn L. Werry Carol Dobson-Stone Olivier Piguet Lars M. Ittner Glenda M. Halliday John R. Hodges Matthew C. Kiernan Clement T. Loy Michael Kassiou Jillian J. Kril Source Type: research