The prognostic role of hepatic venous pressure gradient in cirrhotic patients undergoing elective extrahepatic surgery

Cirrhosis is a life-threatening condition and a major cause of morbidity and mortality worldwide. Improvement in the management of its related complications, of its aetiologies (i.e. viral eradication), and the option of liver transplantation have increased life expectancy of patients with cirrhosis. In this setting, it is not unusual that patients with cirrhosis are proposed for major surgical procedures for orthopaedic, malignancy or cirrhosis related complications. In fact, patients with cirrhosis have a high incidence of gallstones and abdominal wall hernias that require surgical repair[1 –4].
Source: Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research

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Publication date: Available online 16 August 2019Source: Carbohydrate PolymersAuthor(s): Lin Huang, Ziyu Zhu, Dongwei Wu, Weidong Gan, Shanshan Zhu, Wenqiang Li, Jinhuan Tian, Lihua Li, Changren Zhou, Lu LuAbstractVarious functional active hydrogels have been widely applied in tissue regeneration, especially in fields of wound repair as they are similar to the natural extracellular matrix (ECM) and can maintain moist at the wound site. However, preparing a hydrogel with multifunctional properties including high mechanical properties, excellent biocompatibility and long-term antibacterial activity is still a challenge. Here...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
CONCLUSION: In this study, elective neck dissection did not appear to alter survival outcomes or complication rates during salvage laryngectomy. Given the small but significant risk of occult neck metastases, its true value remains unclear. PMID: 31434593 [PubMed - as supplied by publisher]
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
Authors: Ozen S, Akinci B, Oral EA Abstract Lipodystrophy is a heterogeneous group of disorders characterized by lack of body fat, which can be genetic or acquired. Lipodystrophy is associated with insulin resistance that can develop in childhood and youth, and usually leads to severe metabolic complications. Diabetes mellitus, hypertriglyceridemia, and hepatic steatosis ordinarily develop in these patients, and most girls suffer from menstrual abnormalities. Severe complications develop at a relatively young age, which include episodes of acute pancreatitis, renal failure, cirrhosis, and complex cardiovascular dis...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Publication date: Available online 22 August 2019Source: Actas Urológicas Españolas (English Edition)Author(s): L.E. Garcia, J. Gonzalez, G. Serena, M. Ammar Al-Nuss, M. Morsi, W. DeFaria, G. Ciancio
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Source Type: research
Publication date: Available online 22 August 2019Source: Journal of Pediatric Surgery Case ReportsAuthor(s): Kendall M. Lawrence, Matthew Iyer, Prerana Baranwal, Aliza Solomon, Nitsana A. SpiglandAbstractIngestion of neodymium magnets carries risks of dangerous intestinal complications including necrosis of the intestinal wall, bowel perforation, enteroenteric fistulae, and even death. Prompt endoscopic or surgical removal can prevent these complications. Here we report a case of unwitnessed ingestion of 19 neodymium magnets that went unrecognized for two weeks before presenting with small bowel obstruction due to a phytob...
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
Lumbar degenerative disc disease contributes to chronic back pain. Mechanisms of intradiscal degeneration have been linked to genetic, metabolic and mechanical imbalance. Symptomatic relief is influenced by meaningful repair of the annulus and by nucleus supplementation.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Concentrate growth factor (CGF) is a third-generation platelet concentrate that releases a variety of bioactive substances and plays a good role in promoting tissue healing. Bone marrow mesenchymal stem cell (BMSCs) transplantation has been used to treat osteoporosis. However, effect of bone marrow mesenchymal stem cell combined with concentrate growth factor (CGF) on postmenopausal bone defects remains elusive.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Transplantation of adipose-derived mesenchymal stem cells (ADSCs) has become a promising approach for bone regeneration therapies, particularly in elderly patients. However, poor cell survival in vivo after implantation due to the ischemic tissue environment has been one of the major limitations of the effectiveness of this strategy. Hypoxia Inducible Factor-1 α (HIF-1α) plays an important role in angiogenic-osteogenic coupling during bone regeneration, as it is a critical mediator of the adaptive cell response to hypoxia.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Previous reports have shown that treadmill training after spinal cord injury (SCI) contributes to functional recovery and is associated with increased levels of neurotrophic factors in the spinal cord in a rat model. However, the precise mechanism underlying the above observation has not been elucidated. Brain-derived neurotrophic factor (BDNF) is associated with motor function recovery due to its neuroprotective and axon sprouting effects. Promoting BDNF expression in spinal cord lesions by strategies such as physical training and cell transplantation has been reported to be effective in treating SCI in animals.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
A curved –drill guide system was recently introduced to achieve a better trajectory for a low anteroinferior anchor during arthroscopic Bankart repair. However, the clinical performance of such a device remains unclear. The purpose of this study was to evaluate the trajectory and position of the low antero inferior suture anchor with use of the curved-guide system in clinical cases.
Source: Journal of Shoulder and Elbow Surgery - Category: Orthopaedics Authors: Tags: Shoulder Source Type: research
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