White Matter Microstructure in Pediatric Bipolar Disorder and Disruptive Mood Dysregulation Disorder

Disruptive mood dysregulation disorder (DMDD) codifies severe, chronic irritability. Youth with bipolar disorder (BD) also present with irritability, but with an episodic course. To date, it is not clear whether aberrant white matter microstructure – a well-replicated finding in BD – can be observed in DMDD and relates to symptoms of irritability.

https://www.jaacap.org/article/S0890-8567(19)30472-1/fulltext?rss=yes

Source: Journal of the American Academy of Child and Adolescent Psychiatry - July 18, 2019 Category: Psychiatry Authors: Julia O. Linke, Nancy E. Adleman, Joelle Sarlls, Andrew Ross, Samantha Perlstein, Heather R. Frank, Kenneth E. Towbin, Daniel S. Pine, Ellen Leibenluft, Melissa A. Brotman Tags: New Research Source Type: research