In Regard to Zhang et  al

To the Editor: We commend Zhang et  al1 for their recent systematic review of cardiac dose parameters in radiation therapy for non-small cell lung cancer (NSCLC). The authors rightly point out the limitations with the current literature on this topic: study heterogeneity, retrospective data analysis, and multiplicity of testing. We would also argue that the research into cardiac toxicity in NSCLC radiation therapy lacks well-defined hypotheses and research questions. Nevertheless, we do not agree with the authors that no conclusions regarding cardiac dose parameters can be drawn from these studies.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Comment Source Type: research