Two-year analysis of Clostridium difficile ribotypes associated with increased severity

ConclusionsA wide range of C. difficile ribotypes were responsible for C. difficile infection presentations. Although C. difficile-associated mortality has reduced in recent years, expansion of lineages associated with increased severity could herald increases in future mortality. Enhanced surveillance for emerging lineages such as RT220 that are associated with more severe disease is required, with genomic approaches to dissect pathogenicity.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research