Prevalence of submicroscopic malaria infection in immigrants living in Spain

The importance of submicroscopic malaria infections in high-transmission areas could contribute to maintain the parasite cycle. Regarding non-endemic areas, its importance remains barely understood because par...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research

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ConclusionAlthough malaria remains a serious disease affecting millions of people, medicinal plants while used extensively, have not been given the attention warranted for further investigation.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Understanding genomic variation and population structure of Plasmodium falciparum across Africa is necessary to sustain progress toward malaria elimination. Genome clustering of 2263 P. falciparum isolates from 24 malaria-endemic settings in 15 African countries identified major western, central, and eastern ancestries, plus a highly divergent Ethiopian population. Ancestry aligned to these regional blocs, overlapping with both the parasite’s origin and with historical human migration. The parasite populations are interbred and shared genomic haplotypes, especially across drug resistance loci, which showed the strong...
Source: ScienceNOW - Category: Science Authors: Tags: Genetics, Medicine, Diseases reports Source Type: news
CONCLUSION: The VK210 variant is the most frequently observed in the studied region and there is significant genetic variability in the CRR of the P. vivax CSP. Moreover, the antimalarial drug sensitivity profiles of the isolates does not seem to be related to the VK210 subtypes. PMID: 31411308 [PubMed - in process]
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Tags: Mem Inst Oswaldo Cruz Source Type: research
Conclusions: The three-fold hematocrit conversion of hemoglobin estimation is a less reliable method than the measured hemoglobin in anemic children in the study setting.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
Authors: Orwa TO, Mbogo RW, Luboobi LS Abstract The emergence of parasite resistance to antimalarial drugs has contributed significantly to global human mortality and morbidity due to malaria infection. The impacts of multiple-strain malarial parasite infection have further generated a lot of scientific interest. In this paper, we demonstrate, using the epidemiological model, the effects of parasite resistance and competition between the strains on the dynamics and control of Plasmodium falciparum malaria. The analysed model has a trivial equilibrium point which is locally asymptotically stable when the parasite's ...
Source: Computational and Mathematical Methods in Medicine - Category: Statistics Tags: Comput Math Methods Med Source Type: research
Parasite prevalence has been used widely as a measure of malaria transmission, especially in malaria endemic areas. However, its contribution and relationship to malaria mortality across different age groups h...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
CONCLUSION: This study has shown that malaria in pregnancy causes a significant decrease in the platelet count and prolongation in the prothrombin (PT) and the activated partial thromboplastin time (APTT). There is need for the malaria and haemostatic parameters to be assayed routinely on pregnant women particularly those presenting to antenatal clinic with febrile illness. PMID: 31282411 [PubMed - as supplied by publisher]
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
Climate change is the greatest health challenge of the 21st century, and threatens all aspects of society, says the WHO in its COP24 Special Report. What could digital health technologies do to support the fight against the climate crisis? How could healthcare processes, facilities, medical devices become more sustainable? As it is humanity’s priority to mitigate the worsening as well as the impact of rising temperatures and extreme weather events, we tried to figure out what role digital health could assume here. We found many options – and even more possibilities for future development. The climate crisis...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine air asthma climate climate catastrophe climate change climate crisis digital digital health efficient Healthcare mosquito optimize resilience solar sustainability technology Source Type: blogs
Publication date: Available online 31 May 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Lolabattu S. Raju, Shwetha Kamath, Manjunatha C. Shetty, Sanghamitra Satpathi, Akshaya K. Mohanty, Susanta K. Ghosh, Nikunja Kolluri, Catherine M. Klapperich, Mario Cabodi, Govindarajan Padmanaban, Viswanathan A. NagarajMalaria continues to impact global health, and developing ultrasensitive methods capable of detecting submicroscopic parasitemia—a challenge that persists in low transmission areas, asymptomatic carriers, and patients showing recrudescence—is vital to achieving malaria eradication. Nucleic acid a...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
Authors: Thellier M, Simard F, Musset L, Cot M, Velut G, Kendjo E, Pradines B Abstract In 2015, 212 million new cases of malaria were reported, causing 429,000 deaths. The World Health Organization (WHO) estimated a 41% decrease in the number of new cases worldwide between 2000 and 2015. The number of deaths from malaria fell by 62% worldwide and by 71% in Africa. In mainland France, malaria is mainly imported by travelers or migrants from endemic areas, in particular sub-Saharan Africa (95%). In France, the number of imported malaria cases, mainly due to Plasmodium falciparum (85%), was estimated at about 82,000 f...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
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