WT1 in astrocytomas: Comprehensive evaluation of immunohistochemical expression and its potential utility in different histological grades

CONCLUSION: This study supports the oncogenic role of WT1 in astrocytomas. WT1 was found to be valuable in distinguishing different grades of astrocytomas. WT1 can aid in differentiating neoplastic process from reactive gliosis, particularly in recurrent tumors. Higher expression in glioblastomas supports its immunotherapy potential.
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research