A Case of Eosinophilic Esophagitis Associated with Herpes Esophagitis in a Pediatric Patient.

A Case of Eosinophilic Esophagitis Associated with Herpes Esophagitis in a Pediatric Patient. Clin Endosc. 2019 Jul 17;: Authors: Kim J, Lee K, Lee W Abstract Eosinophilic esophagitis is a rare disease in Asian countries, but its incidence is growing rapidly in Western countries. The main pathophysiology of eosinophilic esophagitis is esophageal epithelial barrier dysfunction; disruption of the esophageal epithelial barrier easily induces antigen sensitization to foods and aeroallergens, which leads to subsequent esophageal inflammation as a result of eosinophil recruitment. Here we report a case of an 11-year-old Korean boy who suffered from fever, odynophagia, dysphagia, and chest pain. His upper endoscopic findings showed longitudinal ulcers with a volcano-like appearance at the distal esophagus. Polymerase chain reaction test results and biopsy specimens were positive for herpes simplex virus type 1. He was treated with acyclovir and a proton pump inhibitor, but his follow-up endoscopy showed typical patterns of eosinophilic esophagitis, and the biopsy specimens were compatible with the diagnostic criteria for eosinophilic esophagitis. Therefore, we report a very rare case of eosinophilic esophagitis after herpes esophagitis in a Korean child with normal immunity. PMID: 31311913 [PubMed - as supplied by publisher]
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research

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Authors: He J, Song P, Kang Q, Zhang X, Hu J, Yang Y, Tang M, Chen D, Hu S, Jin C Abstract China has initiated the special security project for rare diseases from the national strategic level since 2018. Chinese government has formulated China's First List of Rare Diseases (121 diseases included), established Expert Committee of Diagnosis, Treatment and Security of Rare Diseases and China Alliance of Rare Diseases. The government also encouraged all the provinces to include the security plan and strategies of rare diseases into key work and promoted the establishment of rare diseases clinical research center and th...
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
ConclusionOverall, the number of complaints was significantly reduced. Only in the case of persisting adenomyosis patients suffered from ongoing postoperative complaints, as in reproductive aged women keeping the uterus was highly required. Although this pilot study about systematic posterior peritonectomy showed improved recurrence rate and fertility rate, the main question remains: does this surgical technique appropriate better results and outcomes in the future. This question has to be addressed in a prospective randomized study.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionMindfulness was previously shown to be a promising intervention for chronic pain treatment. Our study demonstrates that higher pre-operative dispositional mindfulness is associated with more favorable post-operative pain outcomes, including lower pain scores, but not lower opioid consumption. This relationship provides an opportunity to target the modifiable personality characteristic of mindfulness, to improve post-operative pain for patients planning gynecologic surgery.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
With tensions over trade with China escalating, President Donald Trump said on Friday that he is “ordering” the U.S. postal service and express shipping companies to “SEARCH FOR &REFUSE all deliveries of fentanyl,” a deadly synthetic opioid. American officials have long blamed China for the influx of fentanyl and related drugs reaching U.S. borders — sent directly and trafficked via other countries — while federal efforts to limit (if not stop outright) their import have long been underway. ….your companies HOME and making your products in the USA. I will be responding to C...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China Drugs White House Source Type: news
This study is registered with ClinicalTrials.gov, number NCT02176382.FindingsBetween Oct 15, 2014, and June 10, 2016, 269 women were assessed for eligibility. 76 participants were randomly assigned to 20 μg teriparatide (n=39) or 40 μg teriparatide (n=37), of whom 69 completed at least one post-baseline visit. At 15 months, mean spine aBMD had increased to a significantly greater extent in the 40 μg group (17·5% [SD 6·0] increase) than the 20 μg group (9·5% [3·2]; difference 8·1%, 95% CI 5·5 to 10·6, p
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Researchers assessed 2,000 people on waiting lists and found that about 20 per cent reported being in extreme pain. And, as I saw with my gran, this can have a massive impact on their mental health.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 22 August 2019Source: CellAuthor(s): John V. Lin King, Joshua J. Emrick, Mark J.S. Kelly, Volker Herzig, Glenn F. King, Katalin F. Medzihradszky, David JuliusSummaryTRPA1 is a chemosensory ion channel that functions as a sentinel for structurally diverse electrophilic irritants. Channel activation occurs through an unusual mechanism involving covalent modification of cysteine residues clustered within an amino-terminal cytoplasmic domain. Here, we describe a peptidergic scorpion toxin (WaTx) that activates TRPA1 by penetrating the plasma membrane to access the same intracellular site...
Source: Cell - Category: Cytology Source Type: research
Authors: Deer TR, Malinowski M, Varshney V, Pope J Abstract INTRODUCTION: The choice of the proper intrathecal drug to treat neuropathic pain has been subject to much debate in recent years. Areas Covered: Currently, the United States Food and Drug Administration (USFDA) has approved two drugs for chronic intrathecal use for the treatment of pain, however, there has been substantial growth in the development of other intrathecal drugs that can be used for neuropathic pain. We performed a PubMed literature search looking at intrathecal drug research for neuropathic pain between January 2005 to May 2019 and discuss c...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
ConclusionsOpioid dependence in the over 65-year old population after lung resection is high but was significantly lower among those who received minimally invasive surgery, in addition to other factors.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Pushups are a beneficial exercise that people can do every day. Pushups can increase muscle mass and cardiovascular health. Risks include back pain. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Sports Medicine / Fitness Source Type: news
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