Hereditary persistence of alpha-fetoprotein: a rare cause for unexplained alpha-fetoprotein elevations in pregnancy.
Hereditary persistence of alpha-fetoprotein: a rare cause for unexplained alpha-fetoprotein elevations in pregnancy.
Conn Med. 2013 Jan;77(1):43-5
Authors: Rood K, Stiller R
Abstract
Markedly elevated maternal serum alpha-fetoprotein (MSAFP) levels were found in a 26 year old healthy, nulliparous Polish woman during pregnancy. No fetal abnormalities were identified on targeted ultrasound and amniocentesis revealed normal amniotic fluid alpha-fetoprotein (AFP) values. Maternal ultrasound screening for liver and ovarian germ cell malignancies were also negative. The mother delivered a live, healthy female at term and a repeat maternal serum AFP postpartum remained markedly elevated, suggestive of hereditary persistence of alpha-fetoprotein.
PMID: 23427373 [PubMed - in process]
Source: Connecticut Medicine - Category: Journals (General) Authors: Rood K, Stiller R Tags: Conn Med Source Type: research
More News: Amniocentesis | Cancer & Oncology | General Medicine | Liver | Ovaries | Pregnancy | Ultrasound | Urology & Nephrology